Convenia Long-Acting Antibiotic Injection

“Awwww, Doc, can’t you just give him a shot?”

Usually that question comes from a pet lover in the form of an objection to having to give oral medications for a two week or longer time period. Up until now our answer has been, “No, an antibiotic injection will last 12 to 24 hours, then we would have to give another one. Do you want to come in every day for 14 days for injections at $35.00 each?”

But the times, they are a’changing.

Enter Convenia, (cefovecin sodium) the long-acting antibiotic from Pfizer Animal Health that lasts 10 to 14 days with a single injection. Convenia is more than just penicillin. It’s a broad-spectrum antibiotic (in the simplest terms that means it kills a lot of different kinds of bacteria), so it can be used in a wide variety of infected organ systems and clinical and hospital situations.

Convenia isn’t right for every infection. If it were, it would be the only antibiotic on the market. Instead, there are hundreds and hundreds of antibiotics, each with a situation or organism on which it works best.

If my pet were a patient, I would sure ask my pet’s doctor if Convenia (cefovecin sodium) were right for him.

covenia, convina, convinia, covinia

237 Comments to “Convenia Long-Acting Antibiotic Injection”

  1. Dale 10 June 2014 at 3:39 am #

    My 11 year old cat has been diagnosed as having a low grade urinary infection and Convenia was prescribed. The first injection really helped and she has been far happier since the injection. What puzzles me and concerns me after reading all these posts, is that she has prescribed another injection to be given 2 weeks after the first,(which is now) without any further urine tests being done. How advisable is this? I am especially concerned considering the Convenia stays in the system for 2 months, the age of the cat, and the fact that I was told it was a low grade infection (staphyloccocus schlefii schlefii).

    • Dr. James W. Randolph 13 June 2014 at 10:30 pm #

      On this page, press Ctrl-F (Command-F on a Mac) and type in deep breath, then press the Enter key. The advice I gave Luccianna also applies in your situation, I believe. Then, Page Up and read Lucianna’s reply to me. I am confident that your kitty will be better, and, if he isn’t, it won’t be because Convenia was at fault. If she’s not better in a few days she will require additional testing to determine what contributing factors are in play. Sooner than a few days if she seems a lot worse. Please write back and let me know how she does.

      • Dale 16 June 2014 at 10:17 am #

        Many thanks, Dr Randolph, my kitty seemed fine but I must say once the 2 weeks was up she seemed a little under the weather again. My veterinarian gave her the second injection as my he suggested, and she seems fine again. My veterinarian seems happy that the second injection will do the trick – do you agree or should I have her urine tested again to be sure? (Will it have to be the needle directly into the bladder test or can I get away with catching a free flow sample?). I know it sounds odd – first I don’t want to give her a second injection and now I am asking if I should give her a third, but I just want to be sure she is clear of any infection.

        • Dr. James W. Randolph 16 June 2014 at 11:19 am #

          Testing after urinary tract infection is crucial, Dale. Click here to read all about that concept. Be sure to click here, too, to read and understand that not all urinary tract inflammation in cats is infection. Hill’s Pet Nutrition has come out with a new form of their classic c/d, which they call Stress Formula. I haven’t written about it yet, but it contains natural ingredients to reduce the stress that is believed to play a part in so-called interstitial cystitis. Ask your veterinarian if this food might be right for your kitty. As to whether to have the urine specimen obtained by cystocentesis or CCS (clean catch midstream), that is up to your pet’s doctor. The fact is, however, that pets tolerate cystocentesis extremely well and it is the best way to avoid accidental contamination of the urine specimen.

          • Dale 20 June 2014 at 3:11 am #

            Thank you so much Dr Randolph. She is currently eating Hills c/d and Hills j/d as she also has bad joints, but I will ask my vet about the Stress Formula. She has been slightly stressed ever since we were adopted by three 3wk old kittens 3 years ago, so that may be just what she needs.

          • Dr. James W. Randolph 20 June 2014 at 11:01 am #

            I am delighted that we were able to help. Thank you for reading, Dr. Randolph.

  2. Maria 1 June 2014 at 3:19 am #

    Should the pet be monitored after Convenia shot and before leaving vet? I would be concern of a particular pet having a negative reaction shortly after the shot.

    • Dr. James W. Randolph 1 June 2014 at 1:59 pm #

      Maria, I have used untold quantities of Convenia, and I have seen one (1) reaction, which was clearly an allergic response by the way it presented in the patient. The little Cocker spaniel responded quickly to usual allergic reaction protocol with no sequelae. So, if you had nothing better to do than hang out at your veterinarian’s office for 15-20 minutes, that would be an abundance of caution, but otherwise, no, I do not recommend monitoring of any kind, and neither does the package insert for the product. I reported the incident to Pfizer Animal Health (now Zoetis) and they informed me that such allergic reactions are quite unusual with Convenia. Thanks for reading, Dr. Randolph.

  3. pj 30 May 2014 at 7:22 pm #

    Thank you Dr., for this great site. I’d like to share a little history and a few questions, if that’s OK.
    I adopted 2 feral-caught “twin” brothers 12 years ago. They have been my joy. While their gray/white tuxedo markings were identical, one had long hair, and was built like a tank, the other was more lithe and had short hair. And they were inseparable.
    Unfortunately, the last few years have been desperate financially, and I wasn’t able to continue with their check-ups.
    2 months ago, the short hair guy died under circumstances that STILL drive me batty. I noticed he had his 1st claws on each front paw were becoming ingrown. I took him right to a veterinarian, who fixed the claws, gave him an antibiotic, and said he had a heart murmur.
    Within 24 hours he was almost catatonic, eyes fixed and dilated, hiding under a chair and growling. This was fee I could not afford the sweetest indoor cat, so no rabies.
    In the middle of the night I took him in (for an emergency fee I could not afford) and was told without $1000.00 dollars of tests, nothing they can do but try an anti-nausea and pain shot.
    OK I was desperate as he got worse. Found a home veterinarian – she came over, took one look at him and says: “He’s had a stroke, watch, he’s seizing.”
    They gave him a steroid shot, and I’d fed him for a day with the syringe, but he was done.
    He did begin to seize and within 24 hours he’d had 3 massive ones and was dead. Nails clipped on Tuesday. Dead Sunday at 7 AM. Thank God for the home veterinarian, who was on the phone with me much of the time in the last hours.
    So, I’m still spinning over that, and last night his brother stopped eating, is weak, listless. Took him to the home veterinarian’s hospital and the veterinarian was very understanding. Gave him Convenia and we’re waiting for blood tests.
    I’m feeding him baby food; he won’t touch cat food.
    I’m praying this can’t be happening again so soon.
    Thanks anyone any thoughts on any of this. It’s a bit unreal for me.

    • Dr. James W. Randolph 31 May 2014 at 2:29 pm #

      What a sad story, PJ! You have done your best and you “bought” some really good quality time for these two, who would otherwise have lived the miserable existence of a feral cat (not that they know it’s miserable, they are probably just happy to be alive, unlike us humans who would wallow in our misery.). Unfortunately, as your emergency clinic pointed out and your house-call veterinarian supported, without appropriate diagnostics the best we can do is perform a thorough physical examination and, using the information provided, create a treatment profile based on that. We must recognize that, in many cases, more information is needed to make an accurate diagnosis and proceed to effective care. Sometimes such symptomatic treatment is effective. Sometimes it is not because we could have had more specific treatment if we had the input of more information. So, I have the information you have provided, but the list of differential diagnoses is so long for those symptoms that you’ve given that it is impossible to narrow that list. I wish I could help more, but I would have to be there where your kitty to examine him, at least as a beginning. Please keep us posted on his progress. Best wishes, Dr. Randolph.

      • pj 31 May 2014 at 4:27 pm #

        Thanks Doc. This morning the vet told me his bloodwork confirms his kidneys are failing.He said barring a transplant we have days or weeks. He’s only consuming cat formula today.I’m going to keep watch and have the home vet come when it’s time. Thanks again.
        PJ

        • Dr. James W. Randolph 1 June 2014 at 1:48 pm #

          I am so sorry to hear that your little baby isn’t going to make it. You have done an excellent job of taking care of both of them. Our prayers are with you. Click here to read about kidney failure. Dr. Randolph.

  4. Margaret Brown 26 May 2014 at 5:32 pm #

    I have a cat who needs tooth extractions due to gum disease. She is 12-13 years old. I tried giving her a liquid antibiotic and was able to get 2 doses per day down her for 7 days and one on the 8th. Then she started hiding, and I could not finish the dose. Can she get an injectable antibiotic before and after her surgery, so I don’t have to try to give her anymore myself? I accidentally got some in her eye one time, because she fights me so hard, and it’s been swollen and bleeding off and on for over 3 weeks now.

    • Dr. James W. Randolph 28 May 2014 at 1:57 pm #

      Only the veterinarian treating your kitty can answer the question of what medication your pet can have. However, if he uses Convenia she would not need an injection both before and after her dental procedure, because one injection keeps therapeutic levels of antibiotic in her systems for 14 days. If your pet’s doctor is not yet using Convenia, he may be able to obtain enough for your kitty from a nearby colleague.

  5. xnikkibobikkix 21 April 2014 at 12:34 pm #

    My cat had PU surgery a week and a half ago, since then, he obtained a bladder infection (UTI) (three days ago) and was given a shot of Convenia to clear it up. The shot worked very quickly for him – mind you, he was back at the vet’s less than 24 hours after we noticed the infection (blood in urine, frequent litter trips etc), so we caught it fairly early. I noticed improvement in his blood-urine and peeing after a few hours of the shot (he had quite a bit of blood in his urine before and it was greatly reduced within 2 hours). He is still recovering from the PU surgery so he is confined to the laundry room with light coloured sheets around so we can monitor everything – that made it reallllllly easy to catch his infection quickly and monitor that as well now.
    My worry: the Convenia reduced the blood in the urine VERY quickly. Is this normal? I guess after reading all these crazy stories about Convenia, I started to wonder if perhaps he is becoming anemic and that’s why the blood in urine reduced so quickly. Am I being crazy?? These bloody horror stories on the internet are enough to drive any pet-mom crazy.

    • Dr. James W. Randolph 21 April 2014 at 2:04 pm #

      It’s certainly not impossible for your kitty to become anemic from blood loss. And, it’s a danger worth watching. If he is anemic you will notice a proportional decrease in activity level and appetite, possibly faster breathing. We perform perineal urethrostomy on patients whose bladder disease cannot be managed medically. Those patients inherently will be more likely to develop blood in the urine, with or without infection. It takes so few red blood cells in even a large quantity of urine to make it look bloody, that it’s unlikely anemia would cause a change in the observable level of color. If in doubt, ask your veterinarian to perform an in-house test called “microhematocrit,” which will quickly tell him the percentage of the blood that is red blood cells. If that number is too low, a diagnosis of anemia is made. He would then seek to find the cause of the anemia. Continue to be vigilant but do not worry yourself to distraction. Keep in mind that 64% of the medical information on the Internet is either outdated, or outright wrong.

      • xnikkibobikkix 21 April 2014 at 3:19 pm #

        Yes it was after his 4th blockage that our vet had suggested the PU surgery, as he was on the proper diet and still managed to get blocked up – the week of his surgery he had 2 blockages back to back in 24 hours so we had decided that the best course of action for him was the surgery. I hate seeing him in so much pain, not to mention, being catheterized time and time again isn’t pleasant.

        I am monitoring closely anyways since he is still recovering from the PU surgery. Its been two days since the convenia shot, he is eating just the same and will get up to use the litterbox or eat no problems. He isn’t so active, but hes never been a really active cat, and to be honest there really isn’t much to do in his recovery room – we were trying to cut back activity so he can recover from the surgery properly.

        He has his check-up on Thursday for the PU, so providing we don’t have any issues until then, he will be getting a urinalysis and blood test then. I will bring up the ‘microhematocrit’ to them just for my own peace of mind.

        Thank you for that bit of information on anemia and how there would probably not be a huge noticeable difference in the blood-urine level. That relieves me! I will still continue to monitor him closely but lets hope he doesn’t need to go back to the vet until his check-up on Thursday!

  6. tonda groetzinger 7 April 2014 at 1:49 pm #

    Hi there, I am treating a very complicated case. I have a spayed female young cat=age unknown=I have had her for about a year. Her present conditions: asthma and allergies and floating patella in right knee and some in left knee but not as inflamed when it acts up medications: dasquin daily, flovent twice daily, lysine treats and albuteral as needed My question is she has been battling several issues since march 15. We or rather I made the poor choice to show her in the catfancy show in rutland vt but she got very stressed. That weekend she wouldnt eat enough. monday we were home and she still wouldnt eat-she acted normal, drank water, no sneezing no Gi upsets.. tuesday she still wouldnt eat., I then noticed her back end collapsed and she struggled to stand up=I dont know if it was because of the known knee issue, inflammation from being in a cage for 2 days, all the handling back and forth cage to judge etc or just weak from not enough food. I managed to get some treats into her and tuna but very little. Tues night we went to the er. She was diagnosed with pain in knee and think not eating from pain. then when drew blood we had a hard time stopping the bleeding. I was holding her after bloodwork and she bled out of her right leg. I of course applied pressure with towel and hollered and they said it took 3 to 4 min to stop the bleeding.. so we originally were go to treat: subfluids for dehydration, pain meds for obvious pain and lame leg and just try to get her to eat. I asked for antinausa med like cerenia/zofran and they refused. said to use pepcid..ok so now that the bleeding issue reared its head they talked me into leaving her overnight for iv fluids because they wouldnt do subfluids with risk of bleeding..and of course once the iv is running they can do medications..so yes I opted for buprenex, pepcid via intravenous, and electrolites..the bloodwork they did came back low platelets..so now here I am crying thinking I need to put her down because I know this is not a quick fix..but I calmed down..let them take her… So here it is april 7th..that day was march 18th. She ended up staying for 2 days=they got a bone marrow aspiration to make sure she is making platelets etc=yes all normal, did ultrasound on spleen/organs=normal, clotting time test-normal, sent off another bloodwork for manual count of platelets and compplete cbc=normal=no she is NOT anemic. her hemocri is 37-41. they started her on pred on wed nite after bone marrow sample incase immune system mediated=we did 5mg wed march 19th, 10mg thur and fri. fri nite they called said tests came back normal for platelets..at 184,000. ?!? the test in hospital only registered 5,000. they took some on a slide and guessed maybe 30,000 but definately lack of platelets.
    they told me to take her off the pred. do 2.5mg sat and sun and mon. I forgot to give her mondays dose. Then i was supposed to do wed and fri 2.5mg and I felt she was getting icky on the pred so i stopped it=meanwhile she WAS eating better during that time but still in pain. we did the buprenex up to tuesday march 25? I cant remember..they did give me mirtazapine for appetite stimulant as it was starting to lag after the pain meds.. so then on march 30 we went BACK because she was breathing superfast. That day I DID give her a dose-1/4 tab of 15mg and I did see her eating within an hour..so I thought we are done..until the breathing was at 60 a minu..so we went in did xrays-no fluids no nothing other than her classic asthma. she was hydrated and wormy squirmy meowy=they think side effect..so then the next few days went ok, still limp but not bad..she was eating on wednesday 26 so i opted not to do the mirt. thur morning she didnt eat=so I tried to give her more=she spit it out, i crushed in food and gave it..bad mistake..poor cat. so i called the er to get cyproheptadine and they did. When i got home she was lethergic so I called and asked them if i should give cypro=yes and I did..within an hour she came alive..is this normal? so anyways i didnt give it frid april 4th because she was doing well. fri nite she had bad diarea. sat morning april 5th VERY lethergic. I got her to eat baby food..but couldnt get pill in. she spit spit out..so off to er.. They didnt want to do fluids as she wasnt severly dehyddrated=i said but she WONT get up and eat or drink? So they said we can give her the cypro-take her home and see how it goes..i said yes if she DIDNT have massive diareah..she was already tenting of skin on scruff but not on back..they didnt want to do it..so i gently explained my fears of her fading away die from dehydration..so they gave in..gave her 100ml and sent her home..the doctor was pretty mad at me but I told her just do HALF! but it did help..she did eat later that night, did get more diarea and they said no more babyfood..problem is she HATES the texture of canned cat food unless its pudding like. So sunday same thing. lethergic.i had to work and didnt give cypro since at 11pm nite before she had it and i leave at 6am..when got home yesterday she was sleeping in the sun on the window seat..i dont know if she now has a fever, tried the temperature thingy and i couldnt get it to work..kept saying 99.1 and I know thats wrong!! so at 7pm, last night yep another cypro dose, within an hour she ate some food. but still very lethargic but NOT dehydrated YET. this morning I gave another dose,,she is one stuborn cat. spit it out 3 times then wouldnt swallow. I tried the pill popper but I need two hands to open her mouth=she is STRONG!
    so today we are going to my vet and I want to know if we should try a shot of cerenia for nausa, and convenia as she is now snoring pretty bad at night-sneezes sometimes but not offten. has nasal yucks and eye discharge. We are starting lysine treats..got them sat night.. and I also want to know why the cypro perks her up a bit, does it have antihistimine properties to help reduce all the nasal issues? and stimulate appetite? She is pooping ok but still soft but no more diarea. And we have been doing the flovent 250 mcg 2 puffs am, 2 at pm. I only had to use the albuteral thur morning because she coughed.
    history: back in january she started snoring pretty bad,..we tried humidifier, etc and nothing helped..we did 7 days of zirthamax and it seemed to help within 3 days! no snoring and now there is..the only thing that does help is putting nose spray in her nose=its only water /salt nothing else-Its a baby nose thingy and the tip is nice and soft and the spray is very gentle but the poor thing she HATES it..I only do her right side nostrol because she totally fights me to do the other side and in the past this side has been totally blocked. I also want to get xrays of her skull to see if something else in there is causing all these problems..last year her asthma was really bad with high pollen, high humidity etc and then furnace running..I DID buy a high hepa air cleaner big one back in decemeber? or jan? and it does help both of us..I have allergies so if I have issues..normally she does too. anyways my case is complicated and long, she seemed to resolve from low platelets but now has a nasty URI that I suspect is herpes virus due to her symptoms and lack of fever SO FAR! Tonight we are going to the vets to get her looked at for either more fluids, or medicine to help..too late for antivirals I know and nothing that I know of will help other than lysine..which is being given just havent seen any results yet. this poor cat has been lethergic thur, sat and yesterday. today she was ok but I am at work..gonna pick her up, and her sister 15 yr old kitty started getting runny eye last night and dialted pupils..so both are going in tonight. I have 3 cats who do NOT share beds but I HAVE caught the 15 yr old in the 3 yr olds bed..so suspect thats how it happened..giving the 3rd cat lysine all along because she has always had sneezing issues but nothing else-so hopefully I didnt confuse you. the cat that is sick is the youngest with asthma go figure. the other cats are 11 and 15 and all get shots and vet visits twice a year. thank you for any help, yes I printed out your page on URI and will show to vet..who already knows all this anyways but its a shot..thanks for any help, Tonda and sick Honeybee

    • Dr. James W. Randolph 5 May 2014 at 7:15 pm #

      Tonda, you have done an excellent job of presenting Honeybee’s case, and you have written a lot, but I am afraid that it is much too complicated for us to even be able to comment on, especially without the benefit of examining her and looking directly at her laboratory test results. I would, however, be interested in keeping up with her case if you would be able to send us short synopses periodically, we would love to know how she recovers. Best wishes, Dr. Randolph.

  7. Tina 2 April 2014 at 2:25 pm #

    I have a 1 1/2 year old, 11 pound, neutered male mini schnauzer who has a UTI. [EDITOR'S NOTE: Click here to read about Urinary Tract Infections.] He was given a shot of Convenia on Thursday March 27th, 2014. I am wondering how long before his symptoms subside? I have to keep him in the kitchen because of the frequent urinating and blood in the urine. He’s not drinking much water, even though I keep it fresh and filled. I changed his food (per my veterinarian’s instructions) to Prescription Diet c/d. Since this is a long acting antibiotic, will it take longer to show some improvements? Thank you for your help.

    • Dr. James W. Randolph 2 April 2014 at 2:40 pm #

      Unfortunately, Tina, there isn’t an easy answer to your question of “How long?”. That depends on the patient’s immune system status, the pathogenicity of the organism(s) causing the infection, whether the infection is complicated by other factors, such as stones in the bladder, urethra and/or kidneys. You wrote on March 27th, so I would expect him to be better by now, though certainly not cured yet. If you are still seeing blood in the urine, ask for a recheck appointment and your pet’s doctor will likely want to radiograph him (X-ray) for urinary tract stones. I am assuming that he saw struvite crystals on the urinalysis and that was his inspiration for using Prescription Diet c/d (an aside: Science Diet is the Hill’s Pet Nutrition’s non-prescription line of foods.)

      As for the length of time before seeing improvement, Convenia achieves a high blood level very rapidly, so, despite it’s long duration, it has a very fast onset of action, too.
      Please give us an update soon so that we may know how your little schnauzer is progressing, Dr. Randolph.

  8. Allynn 7 March 2014 at 6:25 pm #

    Hi Doctor Randolph and thank you for this wonderful blog. My 8 year old cat, Apricot, was given a shot of Convenia on March 3rd for stomatitis. She hadn’t been eating for at least a month and had gone from 14.5 lbs down to 12. The next two days she started eating again (tuna fish) but then she stopped. She developed diarrhea and I started treating her with Miralax (1/4 teaspoon, twice a day). The diarrhea stopped two days ago but she still hasn’t passed anything. She still won’t eat and I’ve been giving her pedialyte and baby food. She was given fluids on Tuesday. I was able to stay off work this week and take care of her but I need to go back in next week. She is very weak, especially her back legs. She strains at the litter box but produces nothing. I’m convinced her condition is a reaction to the drug and I understand that side effects can happen. Apart from what I’m doing, is there anything else I can do for her?

    Thanks so much for your time
    Allynn

    • Dr. James W. Randolph 14 March 2014 at 4:55 pm #

      Allynn, I can see nothing that implicates Convenia, given that Apricot has a chronic inflammatory disease, stomatitis, has been anorexic for a month and had diarrhea treated with a laxative (Miralax). It is certainly not surprising that Apricot would be weak, given the lack of food intake. This baby clearly needs intensive care, IV fluids, proper treatment for both the stomatitis and the diarrhea. In addition, she probably needs aggressive diagnostics performed to determine the status of kidney function, liver function, electrolyte imbalances and red and white blood cell status and urinalysis. If Apricot’s diagnosis of stomatitis is the kind described in this post, it is a terrible condition in cats that requires aggressive treatment, usually in the hands of a board-certified veterinary dentist. Click here to find out whether there is one close to you, or ask your local veterinarian where he refers such patients when they are in need of more aggressive therapy. If, on the other hand, he is using “stomatitis” in a more general sense, a dentist visit may not be necessary. What is crucial at this point, however, is basic diagnostics and supportive therapy, because it sounds as if Apricot may be slipping away from you. Please keep us posted on her progress with a followup Comment in this section. Best wishes, Dr. Randolph.

      • Allynn 18 March 2014 at 9:23 am #

        Thank you for your reply Dr. Randolph,
        Unfortunately, Apricot died at home last week. She had had subcutaneous fluid injections and I was hand feeding her baby food every couple of hours. In the end, it wasn’t enough.

        I don’t know what killed my beautiful girl but I do not think it was stomatitis. She had blood work done and everything came back normal except for a slightly elevated calcium count. She did not have “bad breath” or an elevated white blood cell count. My vet had checked her teeth and mouth and did not see anything out of the ordinary but thought she might have lesions in her throat. That’s why he gave her Convenia.

        I don’t think my vet did anything wrong but I am, obviously, very sad to lose my girl (she was only 8 years old). My vet suggested a rapidly progressing form of cancer but, again, her white blood count (and just about everything else) was fine. I feel like I did all that I could and I am very glad to have been with her when she passed.

        Thanks you again for this wonderful site. I will certainly be consulting here again in the Fall when I welcome another cat into my home

        • Dr. James W. Randolph 25 March 2014 at 1:37 pm #

          Dear Allynn, we are so sorry to hear about your sweet Apricot’s passing. Stomatitis, directly, is not a killer. But, the many secondary conditions associated with it can be. Without access to her X-rays and laboratory test results, I can’t conjecture what did, but there could be many possible causes. You did what you could and you loved her while you had her, and that’s what’s most important. Click here to read an article I wrote about grieving, let yourself grieve for an appropriate time, then, when you are ready, go and volunteer at your local shelter, or perform some other selfless act in Apricot’s memory. That is the best way to honor her. Thank you for your kind words and your readership, Dr. Randolph.

          • Karen 25 March 2014 at 8:47 pm #

            I am so sorry for your loss of your little Apricot. You baby’s side effects sound like my little man now. The dr is pretty sure it is intestinal lymphoma. In addition he is running a fever and blood in his urine. He is treating him right now for a possible infection with both Convenia and Orbax. The past month we have done just about everything for his diarrhea, dehydration, loss of eating, weight loss, X-ray showing backup in his little system. My little man is 11 years old. We are making him comfortable and treating him. Hoping for the best. My thoughts and prayers to you and your family.

          • Dr. James W. Randolph 26 March 2014 at 9:19 am #

            Karen, thank you for writing to comfort Allynn. Current schools of thought imply that intestinal cancer may be much more common in cats with GI problems than previously thought. Thank you for your prayers for Allynn, we have prayed for both of you, and for your kitty to have peace and freedom from pain. Dr. Randolph.

          • Allynn 2 April 2014 at 11:45 am #

            Karen,
            Thank you for your kind words. I came back to this site to print out Dr. Randolph’s comments to put them in an envelope with my Vet’s sympathy card and the certificate from “Final Gift” to keep with Apricot’s remains. It was so nice to see that you commented.

            I hope your little fellow is doing better. It is so difficult to see our pets suffer. Do all you can for him but be prepared to let him go if you have to. It is so difficult but, ultimately, the last gift we can give.

  9. Ashley H 24 February 2014 at 7:39 pm #

    Dr. Randolph,

    I, like many other posters on your blog want to thank you for your honesty about Convenia.
    My parents always say the internet will always show you “the good, the bad and the ugly”.
    I don’t even know how I stumbled across your blog but I am happy I did, I will continue to use it as a trusted resource. My little Annabelle had a Convenia and Dexamethasone injection for some skin irritation. It is believed to be caused by a food allergy, so we switched her food to a hypoallergenic variety. I would love to read a blog post about what to look for in cat food, it is increasingly important for all consumers to understand not only what is in all the packaged food they consume, but also their furry loved ones. Annie seems to finally be at peace without aggressively licking, scratching and pulling out her fur. After reading some of the negative things on the Internet I was feeling rather anxious about Convenia, then after reading your blog and feeling more confident in my vet’s decision, I felt compelled to say thank you.

  10. Angie 23 February 2014 at 9:18 pm #

    My 6 month old kitten had covenia injection 2 weeks ago and keeps getting swelling in neck leg and now facial swelling how long will this last.

  11. leanneh 2 February 2014 at 2:28 pm #

    Dr. Randolph,
    I’ve been reading your articles on Convenia and I’m hoping you can help me. My 6 year old cat was given a shot of Convenia Thursday AM to help combat an upper respiratory tract infection. He also has a “bad” tooth that is probably going to be extracted, if we can get him healthy. They also gave him a steroid and an appetite stimulant. Thursday and Friday he seemed to be doing better, but for the past two days he has returned to sleeping all the time and moving like he is 80 years old. He has eaten a bit and seems to be drinking more than usual. I’m worried for several reasons, 1) I expected him to get better, not worse after treatment, 2) I know that not eating is very dangerous for cats and can cause liver failure, and 3) when I visited the Zoetis site, who manufactures Convenia, they list the drug as a treatment for skin infections and abscessed wounds in cats, not respiratory infections. I’m trying to figure out if his current behavior is normal for a “recovering” cat and if I just need to give him more time and I’m also curious as to why my vet would give Convenia when my cat does not have a skin infection or wound. I plan on asking them tomorrow morning when they open but I thought I’d ask you as well and get a second opinion. Thank you.

    • Dr. James W. Randolph 2 February 2014 at 7:28 pm #

      Doctors are free to use medications in any way they can medically justify. When Convenia was approved for use by the Food and Drug Administration (FDA), the provision was limited because for every indication, Pfizer Animal Health (now Zoetis) had to perform clinical trials. To obtain approval for every possible use of an antimicrobial drug would be prohibitively expensive (it’s costly enough for two indications!) and would add no value because the FDA already gives practitioners the freedom to use medications for “off-label” conditions (click here to read about extra-label use of medication). A common problem in cats with Upper Respiratory Tract Infection (URTI) is loss of the sense of smell. If a kitty’s nose is stopped up and he can’t smell his food, he probably isn’t going to eat. IF your kitty’s nose is occluded, use a warm, moist cloth to soften the material in the nose and gently remove it with a Q-tip. DO NOT attempt to go up inside the kitty’s nose any significant distance. You are to limit yourself to the outside and just the first part of the nostril you can see. Cats with URTIs often get worse before they get better and often the primary problem is viral (which isn’t affected by antibiotics) and antibiotics, such as Convenia, are used to help control secondary bacterial invasions. There is no way for me to comment specifically on your kitty because I haven’t examined him, I haven’t seen his chemistry profile and I haven’t seen his Complete Blood Count (CBC). HOWEVER, just because he might get worse before he gets better is no reason not to keep your appointment Monday. As you already know, the liver and many other organs can suffer when an illness drags on unnecessarily. Know, too, that many cats with recurrent URTIs are infected with Feline Leukemia Virus. Click here to read about FeLV. If your pet’s doctor wants to run a test for it and Feline Immunodeficiency Virus, be sure to say YES! Click here to read about FIV. Please keep us posted on his progress.

      • leanneh 3 February 2014 at 9:18 pm #

        Thank you Dr. Randolph,
        I figured since it is listed as a broad spectrum antibiotic that it could be used in other ways, I just wanted to be sure. We made a trip to the emergency veterinarian last night. I know I seem overbearing and panicky, but I know my cat and he was NOT improving. They gave him a shot of ampicillin and Metacam and sent me home with Clavamox drops. He isn’t happy about the Clavamox, but the Metacam seems to have helped him a great deal and he is currently sitting beside me on the couch instead of sleeping in a corner somewhere (although he is currently sleeping while sitting beside me). We’re going to schedule him for the tooth extraction and cleaning Friday so hopefully that will take care of the issue once and for all!
        Thank you again for your advice! The stuff online about Convenia can be scary, but I’ve had two cats get the shot and (knock on wood) they’ve done fine with it and I don’t have to torture them with pills or liquids.

        • Dr. James W. Randolph 5 February 2014 at 2:32 pm #

          Sounds like we are making progress, Leanne! Great news. Please keep us posted on how he does.

  12. Maria 21 January 2014 at 11:56 am #

    I just went to the veterinarian because one of my 13.5 year old cats has a skin issue. He is scratching and grooming his face to the point where the skin over his eyes is scabbed. He has even rubbed a part of his front paw raw. The veterinarian thinks it is an allergy and ruled out fleas and ear mites. She gave a Convenia injection for a cat who weighs less than 15# and then she also gave a dexamethasone injection. From my own internet search, I understand the “Dex” is a steroid and Convenia an antibiotic. My main concern is the assistant asked the veterinarian if 12 was too much “Dex” for my cat? The assistant said, “Are you sure that is not too much?” And the veterinarian reassured her 1 per lb. My cat is 12 lbs and the assistant again questioned the veterinarian saying, “But that is 3 cc?” And the veterinarian said go ahead. How is a regular everyday person supposed to understand all this, let alone try to advocate for their pet? Thanks for your help.

    • Dr. James W. Randolph 22 January 2014 at 12:25 pm #

      Your tale is an interesting one, Maria, and I thank you for sending it in. I don’t see that you have too much to worry about, IF the assumptions I’m making are correct. 1, Ear mites are a VERY UNcommon problem in indoor, adult animals. Click here to read more about that. 2, In our hands, Convenia has been a very safe and very effective antibiotic. 3, (this is actually assumption #1), if the dexamethasone you reference is dexamethasone sodium phosphate, it is commonly used for itchiness problems. 4, If the “12″ you reference is 12 milligrams (mg.), it is a high antiinflammatory dose. Not unsafe, if used infrequently in a healthy patient, but higher than the “everyday” use of dexamethasone sodium phosphate. 5, The 3cc you reference would correlate to 12 mg. of dexamethasone sodium phosphate in its usual concentration of 4 mg/ml. I have never seen any other concentration of dexamethasone sodium phosphate. 6, The only other issue I see here is that I would not have had the discussion the veterinarian and the assistant had in front of a client, but that doesn’t make her a bad veterinarian or the assistant a bad helper. Just a difference in style, possibly. It didn’t seem to boost your confidence in the team, but, that doesn’t make it a bad team, either. The most important factor going forward is that your kitty gets well and doesn’t have ongoing problems. Or, if he does, developing a plan to manage the problem in a healthy fashion. Thanks for reading MyPetsDoctor.com, Dr. Randolph.

      • Maria 23 January 2014 at 9:03 am #

        Thank you for your response and concern, Dr. Randolph. It is comforting and assuring to have your genuine expertise in this forward manner. I really appreciate you compiling these responses and have learned much regarding dermatology and convenia. Yes, my cat did get an injection of Convenia as well as 3 cc or 12 mg of Dexamethasone.

  13. kgrbesic 13 January 2014 at 8:15 pm #

    Dear Dr. James W. Randolph,
    A little over a month ago my 8 year old domestic short hair cat Cindy started isolating herself from her siblings. She started defecating outside of the litter box. I took her in for an exam (under anesthesia because she is an unruly patient). I was told that they were able to do a thorough exam and that her anal glands were pretty full. They expressed her glands and we went home with the thought that she would be fine. Cindy spent an excessive amount of time grooming her backside and after a week I called the veterinarian because she was still isolating herself and her back side looked very uncomfortable. I was given a cycle of steroids and an antibiotic (clindamax?) to help with the inflammation and possible infection. Another week went by and noticed that Cindy wasn’t eating. I took her back in and she was cooperative under exam without being put under (unusual for her). They expressed her anal glands again and found that they were full. We went home with a steroid/antibiotic cream and a stronger antibiotic Zeniquin. After a week Cindy started to flick her back legs whenever she stood up to walk. She was still not eating and would only get up to drink water. She was also eliminating outside the litter box still. It was suggested that I continue on the steroid, the veterinarian thought that she was in pain and that the steroid would help. Two days ago I took Cindy back in because she was very thin and I thought she was in liver failure. Her bloodwork came back with a slightly elevated white blood cell count and her X-ray looked great. The doctor thinks that Cindy is in pain and therefore won’t eat. She injected her with intense steroids (8 week dose) and antibiotic. She is still not eating and now I don’t think she has used the bathroom in two days. I know you have’t seen her, but can you give me your thoughts?

    • Dr. James W. Randolph 14 January 2014 at 4:01 pm #

      Katrina, I don’t say this very often, but I would seek another opinion. While it might require another sedation/anesthesia, it doesn’t seem that your current doctor is reaching the heart of the problem in this situation. Also, try to take her in with a full bladder so that she can have a good chemical and microscopic urinalysis. Or, leave her with them long enough for her bladder to refill. There are so many differentials that I couldn’t begin to give you a reasonable-sized list. Please DO keep in touch and let us know what the second opinion turns out to be. Best wishes, Dr. Randolph.

  14. Kathy Maloy 5 January 2014 at 2:58 pm #

    My 14 year old cat had a shot of Convenia 3 days ago for an abscessed tooth. He seemed like he was getting better and started to eat but today he is acting differently again and has not had a bowel movement in 4 days. Any advice would be greatly appreciated.

    • Dr. James W. Randolph 5 January 2014 at 3:06 pm #

      Kathy, there are many variables in your kitty’s situation, but one thing is for sure: if he hasn’t had a bowel movement in 4 days because he hasn’t eaten in 4 days, he needs to go back and see his doctor. If he is eating a normal amount and isn’t passing stool, especially if he is obese, he should see his doctor. Cats who don’t eat predispose themselves to liver disease, so that must be addressed. It could be as simple as dehydration, or far more serious.

  15. Adele 26 December 2013 at 5:46 pm #

    Hello Doctor, I have a 7 month old Eastern European Shepherd. She started coughing 2 weeks ago. We visited a veterinarian who did a test that diagnosed her with the distemper virus. She was given an unknown shot at that time. Then a week ago I took her to another veterinarian who made an X-Ray, a lab test etc. and he confirmed the distemper. She was given a Convenia shot with B complex vitamin that day. She is still eating good. Mucous and dryness in her nose are noticeable. Her respiration is bad. She hardly wants to go out . I have read that distemper is a fatal disease. What are her chances to live? Do I have to give her another Convenia injection?

    • Dr. James W. Randolph 26 December 2013 at 8:02 pm #

      Sadly, studies have shown that 64% of the medical information on the Internet is either outdated, or just plain wrong. Canine Distemper is usually a survivable condition, with treatment. Some patients can be left with neurologic deficits, but not always. “What are her chances to live?” Without having examined your pet, I cannot say. Statistically, the chances are good, in general, but for your individual pet, you would need to ask the veterinarian who is treating her. “Do I have to give her another Convenia injection?” Fortunately, this is not a decision you will have to make. Your veterinarian will make that decision and advise you. He will also administer the injection, if he deems one is needed. It is not a medication that pet owners administer at home. Please give us an update and let us know how she does, and do not hesitate to contact us if you need more help. Dr. Randolph.

      • Adele 27 December 2013 at 2:28 am #

        Dear Doctor,
        Thanks a lot for your speedy reply. I will consult again the veterinarian once he is back from vacation. At least you gave some hope after reading all the wrong online info about this disease.
        Happy New Year & many happy returns, Adele.

  16. Leigha 19 December 2013 at 12:26 am #

    My 8 year old cat, Lou, was seen today by the vet due to constant licking and inability to produce much urine. The doctor concluded that he has a bladder infection and gave him a Convenia injection, the only examination they performed prior to this was by feeling his bladder. He said it appeared to be empty and therefore didn’t collect any urine from him. He put Lou on Hills Prescription Diet s/d, he has been eating and drinking as normal since we returned home. What worries me is that cnce he attempts to use his litter box he becomes angry and irritable, hissing/growling, crying out, roaming around grooming himself. Is this a normal behavior after receiving the injection? Shouldn’t the doctor exam him more thoroughly, like a urinalysis? I called the local hospital and they recommended coming in for a catheter.

    • Dr. James W. Randolph 19 December 2013 at 4:23 pm #

      Leigha, I can’t possibly comment on the examination performed, because I wasn’t there. However, I am a huge fan of second opinions, and you have every right to seek one. Please click here to read a post to better educate yourself about Feline Lower Urinary Tract Disease. It is important to understand that an inflamed bladder is not always an infected bladder. Veterinarians commonly treat this condition symptomatically (click on DICTIONARY, above, and scroll down to the definition of symptomatically) when no urine is present in the bladder to obtain a urinalysis. In some cases, we withhold treatment in hopes of obtaining urine for urinalysis, but the patient’s bladder wall is so inflamed that he empties the bladder before sufficient urine collects in the bladder. If symptomatic therapy helps, but doesn’t resolve the problem, OR, if the problem relapses, we can proceed to more advanced diagnostics to look for complicating factors. No treatment will be instantaneous, but if your kitty isn’t showing improvement soon, he should definitely be seen soon for more aggressive diagnostics and/or treatment. Licking the perineal region has nothing to do with Convenia administration, it, and the signs of irritability you are seeing are a result of the inflammation in the urinary tract. Please let us know how Lou does. Dr. Randolph.

  17. Lynn 12 December 2013 at 1:05 pm #

    My 3 year old male cat was recently diagnosed with a UT infection. First the vet tried a shot of Convenia; after retesting the urine still showed crystals, bacteria. Another antibiotic was administered (pill) which didn’t work. The vet recommended we do a weekly Convenia shot for 4 weeks. I did not know how dangerous this drug was for my cat until I did some reserch on-line. I have to follow up with another urine test on Saturday. I also did an x-ray to make sure there were no stones or a blockasge (none showing). If the cat’s urine still shows crystalization, should I continue with the Convenia shots or find another treatment. I also have switched him to Royal Canine SO dry food and Blue walnut cat litter. This UT infection has run almost $800 so far and I’m still dealing with it?

    • Dr. James W. Randolph 12 December 2013 at 1:27 pm #

      Lynn, the first thing to understand is that bacteria represent infection, but crystals represent a mineral problem that may result from improper dietary mineral content or improper pH of the urine. Crystals may also represent stones in the bladder (more common), the kidney(s) (less common) or both. First, click here to read about FLUTD, the syndrome of urinary tract inflammation in cats. Second, click here to read about bacterial culture and sensitivity. This is the test that tells your pet’s doctor whether the antibiotic he is using will be effective on the bacteria participating in your cat’s infection component. BOTH problems must be addressed. Click here to read about the diets we use for problems of this type, HOWEVER, DO NOT SWITCH FOODS WITHOUT YOUR LOCAL VETERINARIAN’S APPROVAL! Failure to use the correct diet can result in treatment failure. FLUTD is a complex condition, but one that is almost always manageable. Let us know if we may help further, Dr. Randolph.

      • Lynn 13 January 2014 at 1:05 pm #

        Dr. Randolph, thank you for explaining to me all the different possibilities when dealing with a UTI. It helped clarify this complex condition. Bow Tie passed his last urine analysis and seems to be doing well on the special SO diet. The Royal Canin SO diet is a little expensive being I have 4 other cats that are also eating the dry food; but if it keeps the UTI infections to a minimum it is well worth the cost. I appreciate your quick response and helping me understand further this complex condition. Lynn

        • Dr. James W. Randolph 13 January 2014 at 8:21 pm #

          You are most welcome, Lynn. I am delighted that we could help and that Bow Tie is on the road to recovery AND prevention!

  18. Luccianna 28 October 2013 at 12:05 pm #

    “I found your Web site one night, hysterical after my cat Booba had been given Convenia, for UTI. You lovingly told me to calm down and that he would be fine, and guess what? He was!!! So much bad stuff online about that particular med, but it was a good drug for us, and fixed his UTI. Thanks for helping me to feel better that evening. Your reply was quick and really helped me chill. Much love!!! Thanks so much”

  19. luccianna ciocci 8 October 2013 at 8:01 pm #

    My beloved booba got this shot today for urinary infection, and I come home and Google it, and now I’m so scared this shot may kill him. The Google return search for this medicine is scary, and if I had known better I’d chosen a more traditional kind of treatment. If your fur baby does have a bad reaction there is very little they can do, because this medicine is long acting. I’m trying to be fair here in my judgement, and anxiety over the administration of this shot. I chose this site to go to, to leave a message because at least some good things are said about this medicine. How often does this medicine kill fur babies? please help. Thank you

    • Dr. James W. Randolph 9 October 2013 at 5:44 pm #

      Take a deep breath. Whenever you go online to look up medical information, keep in mind that 64% of the medical information on the Internet is either outdated or just plain wrong. And, that’s not counting the “stuff” that is written by the opinionated, uninformed element. By contrast, when something we’ve published on MyPetsDoctor.com becomes outdated, we take it down! There is a lot of hoopla about Convenia, but how much has been substantiated by laboratory testing and necropsy? Very little. In the years I’ve administered Convenia for both on-label and off-label uses, I have had ONE (1) bad outcome, which was clearly an allergic reaction, was treated and the patient did great. I have spoken to Pfizer Animal Health (now Zoetis) extensively about the safety parameters of Convenia. They are legally bound by the Federal Food and Drug Administration (FDA) to disclose problems with medications. Usage history simply does not match the vitriol on the Internet. There is no reason to suspect your Booba will have any problems from Convenia, much less die! If you would like to read more of what we have posted about Convenia, simply type Convenia into the SEARCH window in the upper right hand corner of this or any page on MyPetsDoctor.com and press the Enter key. I have written about it extensively because it is a wonderful tool in the veterinarian’s toolbox that does wonders for the vast majority of patients for whom it is used.

  20. […] wasn’t happy about it, but the antibiotic shot he received means I don’t have to pill him twice a day for the next 10 days. That’s a […]

  21. Judy Pugh 27 August 2013 at 1:51 pm #

    I took my 13 year old cat to the veterinarian today and he gave him a shot of Convenia. He has had diarrhea for about a month and he is impossible to medicate, pick up, etc. It was a miracle I even got him in the carrier to go to the veterinarian. Anyhow, is Convenia used to treat diarrhea? He had a temperature of 103 degrees and without doing a lot of tests, the veterinarian wanted to try the Convenia as he thought it was probably an infection. I am a bit confused, however, as I read that a side effect of Convenia is diarrhea.

    • Dr. James W. Randolph 27 August 2013 at 2:18 pm #

      Thank you for your question, Judy. Sometimes difficult-to-handle patients put veterinarians in the position of doing the best they can, even if it is not ideal. That may be the situation here. I cannot say for sure because I’m not there and I’m not examining your kitty. That said, bacterial overgrowth of the intestinal tract is not only a real syndrome, it is fairly common. Please click here to read about how those “side effects” of medications are determined. Other methods of treating your kitty’s diarrhea might involve oral and/or intravenous medications. Will he be home tonight to get his oral medicine? Will he sit still and allow you to administer oral medication? Those are some of the challenges we face in dealing with difficult-to-handle patients.

  22. Veebee 13 July 2013 at 1:18 am #

    My 1 year old dog was attacked by another dog on Saturday and lost an eye. He is in post-op recovery and was doing ok until he began shaking and shivering. I rushed him to our usual veterinarian to have his temperature taken. He had a fever and temperature of 104. The doctor, through a series of questions, realized the operating veterinarian at the emergency hospital did not give him an antibiotic, post surgery (only tramadol and carprofen). So our Doc gave him an injection of Convenia and an injection of a corticosteroid (dexamethasone). He said this would help with the fever and aid in the reduction of swelling of incision (which is already almost healed and ready for suture removal). We brought our pup home and he rested and stopped shaking. However, two days later, he’s begun shivering again. Is this a sign the fever has returned? We have an appointment scheduled for Monday (two days away) for stitches removal and can see our doc then. Should we keep him comfortable until then or rush to a hospital?

    • Dr. James W. Randolph 13 July 2013 at 9:54 am #

      It is an easy process to take your pet’s temperature. Go to any drug or retail store and purchase an electronic thermometer and some thermometer probe covers. Put a little lubricant on the probe cover (K-Y jelly, Vaseline or cooking oil), lift your pet’s tail and gently insert the tip of the probe. 1/4″ to 3/8″ is plenty. If you have an assistant, have the helper hold your dog’s head and gently caress and speak to him. The electronic thermometer will beep when it is finished, and you can take the reading. Normal body temperature for dogs and cats is 101.0 degrees Fahrenheit to 102.5. Most dogs run toward the lower end of that scale. If his temperature is elevated, you should plan to see your local emergency clinic. If not, AND if he is eating, drinking and otherwise acting normal, you can wait until Monday. Please let us know how he does.

  23. Terry Lonergan 11 July 2013 at 8:20 pm #

    About 6 years ago, my then 11 year old kitty was diagnosed via scope (a few polyps removed also) with a Pasteurella bacterial nasal infection which was treated using azithromycin. Several months ago, she started shaking her ears and I took her to be checked and they appeared to clear. However, she started again with the mild fluidy purrs she’d exhibited 6 years ago with the sinus infection. A urinalysis showed blood and white cells. She had a shot of Convenia 13 days ago. Around day 10, the fluidy purr seemed a bit better, but, after my being gone for a few days, on arrival home, I found her purring to be very fluidy again. Should a second shot be given, since the first one did not take care of the problem, and should a second urinalysis be done before having another shot? She has renal disease and has just been diagnosed with hyperthyroidism.

    • Dr. James W. Randolph 12 July 2013 at 10:38 am #

      The decision to repeat the Convenia injection is completely the purview of your veterinarian. However, I have given multiple Convenia injections to many of our patients with complete safety. If you would like to read more about renal disease, click here. If you would like to read more about hyperthyroidism, click here. To read even more about hyperthyroidism in cats, use the search term MMHT4 in the search window in the upper right hand corner of any page on MyPetsDoctor.com.

  24. Xan 16 January 2013 at 1:39 am #

    I have a 15-16 year old cat I adopted last year who seems to have chronic Upper Respiratory Tract Infections. He gets a Convenia injection, and does quite a bit better for 1-2 months, then gets symptoms all over again. Is it OK that he’s getting a Convenia injection repeatedly? I’ve read that even though it’s only active for about 14 days, it’s in the body for 2 months, so now worried that his just getting another injection after just having one just over a month ago isn’t good, though the veterinarian didn’t indicate it should be a problem. As for his chronic URIs, is there anything else I can do to try and get rid of it permanently, or might it just be something we have to deal with in an older cat with possibly weakening immune system? Thank you.

    • Dr. James W. Randolph 16 January 2013 at 12:58 pm #

      Thank you for your question, Xan. Cats infected with Rhinotracheitis, a Herpes virus, will have relapses regularly. Click here to read a comprehensive outline of upper respiratory tract diseases. IF Herpes virus is his problem nothing is going to completely clear the viral component of infection because Herpes “hides” from the immune system in nerve cells and comes out when the immune system is under stress. Age is a common cause of immune system dysfunction in all mammals. Antibiotics cannot help with viral infections, but are crucially important in controlling secondary bacteria. I, too, have found Convenia to be effective in many of these cases, and have more than one patient on long-term, repeated use of Convenia with complete safety. Also, ask your veterinarian about using immune system supports such as Enisyl. Tagamet has been shown to help some of these patients, but you will need to get the proper dose from your pet’s doctor. We wish you well and stay in touch, letting us know periodically how he is doing.

      • Gorgi77 9 November 2013 at 9:36 pm #

        I had my 4 month old kitten at the veterinarian today with 106.7 fever. Bloodwork showed some anemia and low WBC, 3.3. She suffers from FHV more in the eyes(conjunctivitis). Today they gave her a shot of Convenia and she’s so lethargic, and won’t eat. Was it smart to give her a shot because her WBC was so low?

        • Dr. James W. Randolph 10 November 2013 at 10:43 am #

          106.7 is a VERY high fever, even for a kitty. (Cats tend to be able to run higher fevers, on average, than dogs.) She was sick before the Convenia injection, so there is no reason to think the lethargy and anorexia are Convenia-related. When we see fevers, we know there is a source of inflammation, and there is a good chance that inflammatory process is related to infection. If the infection is coming completely from Feline HerpesVirus (FHV), the antibiotic injection won’t help, except to give her protection against future bacterial invaders. That said, a patient with a 106.7 temperature probably has bacteria on top of her FHV already. The WBC may be low because the immune system is in danger of being overwhelmed, in which case she needs all the help she can get to keep the disease process from worsening. Given the information I have here, I’d say your pet’s doctor did exactly the right thing.

          • Gorgi77 10 November 2013 at 11:54 am #

            Thanks so much! Today she is great! Eating, playing and grooming. I think the Convenia helped her! So I shouldn’t scare myself by reading all the negative effects of this med. Glad to be waking up to a lively kitty. Yes, that temperature scared me luckily it went down to normal in 3 hours following an antiinflammatory shot. If she’s an indoor cat how can she get a bacterial infection? Veterinarian didn’t suspect it and said it’s all viral and most likely from the Herpes virus. Hopefully this Lysenix will suppress the virus and this never happen again. I was so scared for Snorkels.

          • Dr. James W. Randolph 10 November 2013 at 12:03 pm #

            Bacteria are everywhere. They’re all over you, they’re all over me, and they’re all over everything in our environments. A good place to grow, like a sick kitty, isn’t hard for a bacterium to find, and it isn’t hard to find the bacteria to fill the bill. Unfortunately, a lot of unqualified people have said some really bad things about an extremely useful tool, Convenia. We are delighted to know that Snorkels is so much better!

  25. Crystal Deuth 18 October 2012 at 4:05 pm #

    I need advice on the Convenia injection for my cat. She went to the veterinarian last year November, 2011. She was drooling and had loss of appetite. Veterinarian said she had a bad tooth but couldn’t diagnose completly due to my cat not cooperating (go figure). Anyway I asked about an antibiotic injection to try first. So my cat was given Convenia and within a day her drooling stopped and she was back to her normal self with no side effects whatsoever. Worked great! Now almost a year later she is not eating again which is VERY unlike her. No drooling this time just the eating issue. She is not acting sick per se but definitely an issue there. I am wondering if it is the tooth or not. So long story short she is going back to the veterinarian and now after reading all the horror stories of the Convenia shot I am very leery to try it again. Please help with any advice! Thank you.

    • Dr. James W. Randolph 18 October 2012 at 4:46 pm #

      Crystal, let’s begin by addressing some basic issues. 1, Your kitty needs a thorough examination to first determine the cause of the problem. If the doctor thinks it’s a tooth issue it’s worth a sedation for a thorough examination to know for sure if there is a tooth problem. When tooth roots become infected antibiotic therapy alone rarely solves the problem. Usually the tooth must be extracted to allow irrigation and drainage of a plugged-up abscess. 2, Just because she had a tooth problem last time (or didn’t, since there was no definitive diagnosis) she quit eating doesn’t mean it’s a tooth problem again, thus, see #1, an examination is imperative. 3, you can read horror stories about anything and everything on the Internet. Just because someone SAID Convenia injured their pet doesn’t mean it’s so. In every case I set out guidelines for what should be done in case of an adverse event. You may click here to read that post. How many of the claims of Convenia injury are backed by exhaustive investigation? None that I have seen. 4, My professional experience with Convenia has been flawless with the exception of a single allergic reaction, which was easily treated with medication and resulted in no other medical problems. I have used “gallons” of it and stand by its safety profile.

  26. Byron 6 September 2012 at 5:34 pm #

    My cat was given this shot for an ulcerated cornea that may be related to having Chlamydia in her eye as a youngster. I am concerned that this is a case of over-treatment; a 2-week antibiotic for an eye infection that was improving? I might have refused but wasn’t told it would last 2 weeks until the injection was underway. A main concern is whether this will destroy intestinal flora like oral antibiotics do?

    • Dr. James W. Randolph 13 September 2012 at 2:24 pm #

      Byron, it’s not unusual for cats with ocular Chlamydia complaints to also have upper respiratory complaints, so I’m guessing (and it is only an informed guess, having neither examined the patient or spoken to your veterinarian) that he was concerned about secondary bacterial infection and chose Convenia for that. While I always give clients a choice between oral medication and Convenia when it is indicated, (especially in cats and frequently in small dogs) almost no one chooses oral medication over Convenia anymore.

  27. Sue Kearney 21 March 2012 at 6:12 pm #

    Our cat suffered with an intestinal infection for 6 months. I took him to a new veterinarian and the doctor gave him a series of two shots of Convenia two weeks apart, and it was like a miracle. The former veterinarian changed his diet, treated him with other antibotics and nothing worked until he received Convenia. We will be forever grateful for this wonderful drug.

    • Dr. James W. Randolph 21 March 2012 at 7:26 pm #

      Susan, as many intestinal problems are related to hypersensitivity to food-related items, your first veterinarian was correct to try a diet change. As often happens, the doctor giving the second opinion has the advantage of knowing what the first veterinarian has tried that didn’t work. Bottom line? Your kitty is better and everyone is happy.

  28. Vickie Malis 12 March 2012 at 7:59 pm #

    My cat Chobe has had chronic pancreatitis for almost 2 years. He is maintained on an oral antibiotic but recently had an acute episode when it got a lot worse. Chobe has now had 2 Convenia injections (I’m getting ready to give him his third injection) and he is MUCH better. His insulin needs have gone back down and he is much more active – almost symptom free. I understand that antibiotics don’t necessarily work for an acute episode of chronic pancreatitis – but it has sure helped my kitty and I thank you.

  29. Cynthia 6 March 2012 at 1:03 pm #

    Hi Doc, my cat was given Convenia for her UTI which was very bad (blood and all) on Friday night and today is Tuesday. I thought she was doing well, until this morning when I saw blood on my floor again. I was so heartbroken all over again. I thought was recovering and now blood again. She is also on methigel, and special food to help her with her UTI. What do you think this could be?

  30. Queen 20 January 2012 at 9:43 pm #

    Im a 10 month greatdane female i need convenia again…my mother put like 3000$ on me since 6 month i had demodex ive been sterilised for less come back of this and after all that i loose my fur my skin is dry i try the natural method since one week…can i die fault of no convenia my weight 120 pound im lazy , anxiety , shake … =( how much for convenia please help be i buy right now i love my mother and she love me im her queen wait for answer thks xx

  31. woody 20 January 2012 at 9:23 pm #

    Nine year old male cat with Crylotkorax. Doctor drained the chest area of cat drawing about eight ounces of fluid. Doctor then give cat Convenia and Vetalog when stable. On hour later cat had rapid breathing and heart rate. Dealth resulted. Any feed back?

    • Dr. James W. Randolph 20 January 2012 at 9:32 pm #

      We are saddened to hear of the passing of your kitty, Woody. I’d be interested to hear your thoughts and what your veterinarian had to say about the cause of death.

  32. Debbie 7 August 2011 at 4:25 pm #

    My 10 week old kitten was given Convenia for a upper respiratory infection. How long does it take to see improvement? He is sneezing and coughing.

    • Dr. James W. Randolph 15 August 2011 at 5:57 pm #

      Debbie, there are so many factors in upper respiratory tract infections of cats there is no way to give a one-size-fits-all answer. Fever, congestion, amount and location of congestion, whether cough is present in addition to sneezing, other complicating factors, such as diarrhea, percentage of illness caused by viral disease versus bacterial disease (I could go on and on). I would say if my kitty were not eating in 3 days or if he were not substantially improved in his respiratory tract signs in a week I’d be on the phone, making another appointment with my veterinarian. Best wishes, Dr. Randolph.

  33. Lexis 11 April 2011 at 4:18 pm #

    My cat Max 19 months old had a large open wound on Friday his skin was torn up and you could could see the muscle on his gluteous. We don’t know how this happen since he is an outdoor cat during the day. We took him to the vet on Saturday and they flush and closed the wound. He also got an injection of Convenia. First when he was examined on Saturday he had a temperature of 103. Is Monday now and his temperature is over 104. I when back to the vet and got another antibiotic injection Baytril and IV fluids. I don’t understand why the first antibiotic Convenia didn’t work since is a long lasting antibiotic? I’m concern about his still fever and how long is going to take to be resolved? Thanks!

  34. Robert 20 December 2010 at 7:05 am #

    Update 2: The barium moved through to her colon over 6 hours. They described this as “slow, but no clear indication of an obstruction.” I brought her home and she is resting. I removed the fentanyl patch and that seems to have helped slightly although she is clearly in discomfort still as evidenced by her whining. Basically, 3 days, $2,000 and many injections and stressful trauma to her later? They still don’t know anything definitive as to a cause. I’m beside myself and inclined to keep her home for awhile longer to see if she improves/develops any appetite. VERY heartbreaking/frustrating.

  35. Robert 20 December 2010 at 12:07 am #

    Dog is in emergency care facility for past 9 hours undergoing barium xrays to check for blockages. So far, no blockage detected and barium is 1/2 thru intestines. Will call in 3 hours for status report and I’m told if no blockage is detected, they will keep her overnight and try to feed her. Until they detect blockage (likely necessitating surgery?) or she eats on her own if no blockage is found, they will keep her there on IV fluids.
    P.S. so far the bill is $2,200 and they still don’t know what’s wrong and she still wont eat or drink on her own.

  36. Robert 19 December 2010 at 5:30 am #

    Help please! My 1 year old German Shepherd stopped eating 3 days ago. 2 days ago she had terrible diarrhea (no blood but mucous), and vomiting all day until she vomited yellow bile. I took her to my veterinarian. He felt her abdomen and she yelped. He did blood work and a stool test and gave her subcutaneous IV fluids along with B-vitamin injection and an anti vomiting injection. He sent us home with carafate and Cerenia. He called next morning with blood/stool results and said he found no organ damage and no worms so he said he “assumes it’s a gut bacterial infection”. My dog refused food, refused carafate and cerenia so I returned to the veterinarian. They took an x-ray and determined there was a lot of gas in her belly and her spleen was quite enlarged. They gave her an injection of Convenia and a fentanyl patch on her skin. I took her home.
    She still wont eat or drink. It has been about 10 hours since the Convenia injection. She’s lethargic, her stomach is rumbling, she wont eat or drink and I’m worried I’m not doing enough. Should I get an ultrasound on her spleen? I believe enlarged spleen can be symptomatic of bacterial infection or alot of other maladies.
    What should I do? How long can a dog survive without food? Should I force-feed her Pedialyte or water or take her to an emergency care for IV fluids tomorrow if she still hasn’t drunk anything? How long should it take for the Convenia to work and if it works will she regain her appetite quickly? Thanks!

    • Dr. James W. Randolph 19 December 2010 at 10:38 pm #

      Robert, there are simply too many unknowns for me to give you meaningful advice. My fear is that your dog may not have time for more trial, and may need the special services of a board certified internist to sort out her specific problems and get her on the road to recovery before she goes so far down that she can’t recover. Ask your local veterinarian for a referral Monday morning, and please let us know what you find out. Best wishes, Dr. Randolph.

  37. patricia 17 December 2010 at 7:16 pm #

    My cat has leukemia. Always gets ut infections. This time they gave Convenia. After 14 days cat has no white blood cells and is anemic. He is dying. They never ran tests before giving him this drug to see how bad his aniema already was.

  38. Inna 14 December 2010 at 10:59 am #

    My 3 month old puppy has kennel cough. The veterinarian gave him Convenia shot for it. It has been 3 days, and he is not getting better. Was Convenia the right choice? I don’t see it mentioned as a treatment for kennel cough on any of the pet forums.

    • Dr. James W. Randolph 16 December 2010 at 10:16 pm #

      Inna, first realize that there is no such thing as “kennel cough.” Click here to read more. Assuming your puppy has an uncomplicated upper respiratory tract infection, no pneumonia, it can sometimes take longer than three days for improvement. Also, especially this time of year, he must be kept in a protected environment, out of the cold, rainy weather. Indoors, in other words. Most cases require a cough suppressant to break the coughing cycle. If he’s not also on one of those, ask your veterinarian. Please don’t read “pet forums” for medical advice for your pets. Ask your veterinarian. Or a veterinarian you trust. If you continue to read http://www.MyPetsDoctor.com and trust us, we believe you will find us reliable.

  39. Annette 9 December 2010 at 8:13 pm #

    My 7 year old male cat was into the veterinarian Nov. 10 because there was blood in his urine. I took a urine sample in and we discovered that he was full of crystals. I was told to administer a pain medication for 3 days – torbugesic – change his diet to Hill’s Prescription Diet c/d and to try and get him to drink more fluids. After a few days he seemed fine but 3 weeks later he was once again having blood in his urine. I took another urine sample in and this time there were no crystals but a bacterial infection. He was given an injection of Convenia and appears to be fine however he still has “some” blood in his urine 6 days after the injection. Is this normal and how long should it take for the blood to clear out?

    • Dr. James W. Randolph 16 December 2010 at 10:02 pm #

      Annette, as you will read in this post the condition your kitty is experiencing is multifactorial. Using Hill’s c/d is a good start, and I often use Convenia as an antibiotic for urinary tract infections. Be sure to have a followup examination of your kitty, along with urinalysis and urine culture and sensitivity, according to the schedule your pet’s doctor recommends.

  40. bill woods 9 December 2010 at 1:14 pm #

    We moved from Long Beach and miss Dr. R. VERY much !!

    Certainly the BEST VET we’ve ever had !!

    Thanks !

    – B and C

    • Dr. James W. Randolph 16 December 2010 at 10:04 pm #

      What a great compliment and how we have missed ALL of you! Best wishes in your new home, Dr. Randolph.

  41. danie 4 December 2010 at 8:09 am #

    Hi Dr Randolph, I have 2 exotic short haired cats (sisters from same litter). One of them has been acting really strange lately, excessive grooming and also licking walls. She is eating ok, but has lost weight over last few weeks. I took her to the veterinarian this morning, she said that her glands were up on her neck, and took some blood for testing. They did FIV and Leukemia while I was there both were negative. They have sent the other blood off for testing. Asha was given Convenia and Dexafort injection. I was just wondering if there are any side effects I should look for and is she ok to still be around her sister? Thank you.

    • Dr. James W. Randolph 16 December 2010 at 9:44 pm #

      IF, and I emphasize IF, we assume that neither cat has a communicable condition, there should be no reason they can’t interact with each other. Typically there are no side effects with Convenia.

  42. Alana 4 December 2010 at 2:41 am #

    Dr. Randolph, My husband took our cat to the emergency veterinarian since it was after hours. Zidi (our cat) was very dehydrated. He was given fluids. Other tests were done and nothing was found. His temp and vitals were normal. He did come home and was acting “normal.” However, he would NOT eat his dry food. He kept crying for us to give him his “sisters” dry food. I called our regular vet in the morning to brief him on what happened. He was surprised with the reaction as well. We have Zidi on a different dry food that he seems to enjoy. My main concern now is his behavior…he is just not acting like the cat I knew from 10 days ago. I can only say that he is acting differently. Any thoughts?

  43. Tania 29 November 2010 at 2:24 am #

    I help care for a large, stable feral cat colony who live around a school here in Albuquerque. Two weeks ago, we re-trapped an already ear-tipped (i.e., already neutered) feral with a terrible upper respiratory infection. He had green gunk coming out of both nostrils, a gunked eye with some clouding of the cornea, and stringy drool hanging from his mouth. I took him to our local humane association clinic for a Convenia injection and concurrently gave him Clavamox for about a week (administered in his food, wasted several doses until he started eating), then Amoxicillin for the second week. He is much better, amazingly so–no more drooling, eye not gunked shut but still a bit cloudy, eating well. However, I can still hear his breathing and when I shine a light I can see some fluid still in his nostrils. Is it advisable to see if the humane clinic will give him another Convenia shot before I release him? Or should I be asking about some other antibiotic because he’s already gotten the benefit of the Convenia? I am very worried about releasing him back to the colony while he still has fluid in his nose/throat, especially because winter is here and it’s bitterly cold at night. However, it’s not humane to keep him confined indefinitely either–maybe for another week or so to help him gain more weight? The colony is regularly fed dry food, but if he gets sick again and can’t smell it he will probably stop eating again. I also wonder whether I need to gradually re-acclimate him to the cold before releasing him after he’s spent two weeks in a warm garage. Thank you so much!

    • Dr. James W. Randolph 30 November 2010 at 9:50 pm #

      Tania, my first concern is about this kitty’s immune system status. Chronic respiratory infection, especially when accompanied by keratitis which may be herpetic and recurrent are strong indicators for immune system suppression. Are funds available for FeLV and FIV testing? Is there money for testing the cloudy cornea for herpesvirus? Is there money for antiviral medications if the test comes back positive? I don’t imagine you’re going to hurt the kitty with another Convenia injection. Lord knows he faces meaner things than that on the street every day! It is possible to do more harm than good when combining antibiotics, and there are more effective combinations than either of the ones you chose. Ask the doctors at the shelter about some other possibilities. Let me know if I may help further, and God bless you for the work you do for these who can’t speak for themselves, Dr. Randolph.

  44. Alana 25 November 2010 at 12:50 am #

    My 17-pound cat went to the veterinarian this morning and was diagnosed with a bacterial infection. (The skin was all pink and irritated on his tummy and underside of his tail). He received Depo Medrol and Convenia. My cat is now lethargic, eyes are a bit glazed, doesn’t purr when I pet him and won’t take a kitty treat. Could he be having a negative reaction to the Convenia? Is this a “normal” reaction to Convenia? Or a combination of the 2 drugs? I am worried. He is just not himself. If he is having a negative reaction, what can the veterinarian do to make him feel better? THANK YOU!

    • Dr. James W. Randolph 30 November 2010 at 9:41 pm #

      Alana, this is not typical for reactions to Convenia. It’s more likely that the infection is causing him to feel bad. Did you call your veterinarian? What did he say? Some cats and some dogs will feel and act lethargic after Depo Medrol injections. Stay in touch with your pet’s doctor. He knows best what his patient needs, as he’s there and actually seeing your kitty and measuring his vital signs. Don’t be hesitant to let the veterinarian perform laboratory testing if he asks. Let us know if you have more questions, Dr. Randolph.

  45. Susan Tonjes 19 November 2010 at 4:57 pm #

    My 8 year old cat was given Convenia to treat a pretty bad bite in the face and subsequent cellulitis (likely a bite from another cat) about two weeks ago. I was so grateful for the long acting injection. Giving this cat a pill, given the bite location on his face, would have been painful, and a challenge. I’m happy to report no side effects, and a full recovery. I have 4 cats, and I will always ask, going forward, if this antibiotic is an option. I am “ok” at pilling my cats, but it is often a little violent, and sometimes, I wonder if I really got it in there:) Then there is trying to get them out from under the bed at pill time. When is Convenia a good choice? When are other antibiotics preferred?

    • Dr. James W. Randolph 21 November 2010 at 10:19 pm #

      Thank you for a great testimonial, Susan. Convenia is a good choice whenever cost is not a factor (in most cats and small dogs oral medications are going to cost as much as Convenia anyway), when the infection being treated is susceptible to the active ingredient in Convenia and, especially, when the patient is difficult to give oral medication to. We hope he heals fully and without complications.

  46. freia 17 November 2010 at 1:56 pm #

    My cat is 16 years old and got a shot of Convenia for anal sac infection. She would not eat for 3 days and had diarrhea. She had to be sedated which is also very hard on her. The veterinarian insists she needs another shot in 2 weeks. Is this true, since it’s so hard on her?

    • Dr. James W. Randolph 21 November 2010 at 10:31 pm #

      Freia, in my experience most anal sac abscesses will heal adequately and resolve infection with 14 days of antibiotic therapy, which Convenia provides (in ideal cases…the range is 10-14 days). The factors to consider are: 1, do we know that her loss of appetite was from Convenia and not from the abscess? 2, Were there possibly other causes for the diarrhea? 3, At the time for the next Convenia injection ask your veterinarian to examine your kitty well first, deciding whether another injection is necessary. Best wishes, Dr. Randolph.

  47. Rachael 14 November 2010 at 12:49 pm #

    My cat Molly had injured one of her rear claws. I took her to the veterinarian and they decided it was best to just leave it alone and let it heal since the upper part of the nail was still there. They gave her a shot of Convenia as a precaution against infection. The nail is healing up just fine but now she has diarrhea. I know this is a potential side effect but she didn’t get full blown diarrhea until a week after her shot. At first it was just slightly mushy poop which has slowly progressed to diarrhea. Everything else is fine. She eats, she drinks, she plays and is otherwise her normal mischevious self. Do you think it could be from the Convenia? I am currently giving her metronidazole with the hopes of it helping to clear things up. I have an IBD kitty and know that the protocol at my veterinarian’s office for a kitty with diarrhea is this particular drug. I just didn’t want to rush her off to the veterinarian to only be given medicine that I already have plus if this is just a side effect of the drug and will clear up on its own then I don’t see a need for a veterinarian visit either. This Tuesday will be 14 days since she has had the shot. If it is a side effect how long will it go on for? If it doesn’t clear up by Thursday I will definitly be calling my veterinarian.

    • Dr. James W. Randolph 15 November 2010 at 12:19 pm #

      Rachael, why not just go ahead and call your veterinarian now, and let him know your kitty is having difficulties? He’s treating your other kitty for IBD, so he knows what medications you have on hand, he will either say that he wants you to use that or he wants to dispense something different or he feels your kitty needs to be seen. Best wishes, Dr. Randolph.

  48. kelly 10 November 2010 at 7:20 pm #

    We had our cats laser declawed 2 weeks ago. We noticed that they felt like they had fevers 6 days later, so I took them back to the veterinarian for fear of infection. Everything looked great, but after doing blood work the found that had a virus of some kind. The veterinarian gave them both Convenia to prevent any infections in the paws, mainly because their immune systems are weak from the virus. But now I’m noticing our 7 month old boy seems to be having labored breathing. He had the shot a week ago. Should I be worried yet? I’m not sure if its a side effect from the medicine or not. He isn’t wheezing nor does he seem to be in discomfort of any kind.

    • Dr. James W. Randolph 15 November 2010 at 12:13 pm #

      Yes, Kelly, you should be worried. It is unlikely that a reaction to Convenia would take the form of labored breathing, but the “virus” (did the doctor say what kind of virus?) could be causing anemia or other problems that are resulting in the breathing difficulty. Please let us know what the doctor says. Best wishes, Dr. Randolph.

  49. Karen 9 November 2010 at 6:16 pm #

    My cat had a superficial seroma drained and it was sent to the lab…no infection.
    She had a temp of 103. The veterinarian said she “looks great, healthy” when we left after the drainage and 24 hrs later I was phoning their office in a panic. She was given Convenia without my knowledge, I was told after my veterinarian returned with her following the drainage. Within 24 hours my cat was a completely different animal when I returned from work. She looked like I pulled her from a drainage ditch. She had a screeching meow. I went online to see read about antibiotic reactions in cats and learned about Convenia. Since my veterinarian was out for two days and I was told to wait by another veterinarian at the office, until the next morning to bring her in…that it would likely be fine to wait. To make a longer story short, my cat had to be hospitalized for almost three days and received a different antibiotics and steroids. She has not recovered…she is home now and is taking steroids and oral antibiotics. She is completely lethargic and I am praying she recovers. It has been one week and she is still sleeping all the time and cannot do anything except lie down. I am certain she had a bad reaction from this “convenient” drug. I really would have like to have known the risks. It is not worth the convenience to go through this kind of anguish now. If this happened to a human…there would be consequences that would make the practitioner more careful.

  50. Kristina 24 October 2010 at 11:55 pm #

    Hi Dr. Randolph, I adopted a 5 year old poodle mix (small) from the shelter here about 6 months ago. Today I just took her to the veterinarian because I noticed her urine had a little bit of white in a small part of it. Turns out she had a very high bacteria level in her urine and a small amount of pus. After running tests and confirming it was vaginitis the veterinarian gave her a shot of Convenia, 80mg/ml, she weighs about 11.4 pounds. This is her 2nd UTI since we’ve come home from the shelter. For the first one they gave me a packets of pills and had me give her one a day. Do you think the Convenia will work for this bacterial infection in her urine as good as the pills? They didn’t give me any details of her urnalysis, just that there was a little white “pus” in her urine which (and I quote) “looked like the bacteria was having a party around”. For the Convenia injection I paid $49, which is fine I’ll pay to my doggy better, but the pills I got previously were much cheaper (I think around $18). I just want to make sure this works and it is the right thing my veterinarian did. I have to take her back in 14 days for another urinalysis test, which will cost approx $100 for the urinalysis test, urine sediment exam, urine specific gravity and medical waste disposal fee (these are all the things they charge for in these urine tests). Does this sound right? Thanks for any help. I just want my dog to not get these any longer, I feel bad for her. Is there any other steps I can take in help with prevention of UTIs? I take her on walks every 5 hours, she always has fresh water. Should I start giving her spring water? I read that is good..but didn’t know if that is accurate information. Thanks for your help.

    • Dr. James W. Randolph 26 October 2010 at 4:46 pm #

      Kristina, this is a hard question to answer. First, vaginitis and UTI are not the same thing. Vaginitis is inflammation of the wall of the vaginal vault. Inflammation may be caused by infection, as well as a number of other factors. Urinary Tract Infection (UTI) describes infection that is affecting the urethra, urinary bladder, ureters and/or kidneys. Laboratory confirmation of bacteria seen on the microscope tells us there are bacteria present, but it doesn’t tell us which part of the urinary tract they came from, OR which antibiotics will work best. For the latter a Bacterial Culture and Sensitivity is required. I usually give clients a choice between Convenia and oral medication and the choice is usually determined by the pet owner’s ability to pay and the known difficulty level of giving pills to the pet. Perhaps you should speak to the doctor in advance if you prefer to have pills. Will the medicine clear up the problem? Without a culture and the known/unknown of complicating factors for UTIs, we just don’t know, but UTIs that don’t respond and stay gone deserve a more in-depth workup as you will read in this post. Best wishes on your dog and please let us know how she does, Dr. Randolph.

  51. Callie 24 October 2010 at 10:39 am #

    Dr. Randolph, my cat, Fang is a rescue from a shelter. He has what I believe is a respiratory infection caused by Pasteurella. He has had blood work, cultures, x-rays and laparoscopy to remove a mass in his sinus cavity. The cultures pointed to Pasteurella. My veterinarian administered the Convenia injection and gave us oral antibiotics, Clavamox. We went through several cycles of the Clavamox to no avail. The Convenia seems to do the trick. Next he gave us Orbax (Orbifalxicin). He has been through two bottles and no improvement. We have been doing this regimen for 9 months now. Finally our veterinarian prescribed the Convenia again, but we are administering it ourselves (veterinarian is an hour away). As I mentioned he always is better after the injection, but as it wears off he goes right back to being in poor shape. Is there any harm in using Convenia forever? Should I expect this forever? Fang is approximately 3 years old and he is a Bengal, possibly a mix, but I think full-blooded. He eats well and is very active. He weighs 10.4 lbs. He just can’t breathe a lot of the time and it breaks my heart. We have another rescue, a Bengal, and he shows no signs of infection. We got him after Fang and seems to have lifted Fang’s spirits. If you have any suggestions I would be forever grateful! Thank you for your time.

    • Dr. James W. Randolph 26 October 2010 at 4:28 pm #

      I don’t think anyone knows what the long-term effects of using Convenia will be. The FDA has approved Convenia for two consecutive injections, but has put no limitations on a time period between series of injections. In other words, if Fang got one injection today and needed another in six months, that would be acceptable to the FDA. That said, as doctors we often operate outside the parameters of label limitations with off-label techniques, described here. So, with owner approval your pet’s doctor could administer a series of Convenia injections beyond the approved two and continue those as long as they are helping. You, of course, in giving your approval, would have to accept the risks. Would I feel safe in taking that step for my own pet? Most likely, given the right circumstances. One factor to consider is that with many of our chronic dermatology cases we use cephalosporin therapy for as long as six months with excellent safety. It is not a huge stretch to assume that Convenia would have that same level of safety. Chances are good that Fang has some other secondary factor going on, such as Feline Viral Rhinotracheitis, Feline Leukemia Virus and/or Feline Immunodeficiency Virus immune system suppression. Enisyl and certain other immune system stimulants may help. Be sure your pet has two FelV/FIV tests separated by two months which agree with each other (both negative or both positive for either or both viruses).

  52. Sharon 19 October 2010 at 10:59 am #

    My mature male cat has had 3 injections of this medication. The most recent was the 12th of October. He now has developed, since the last injection, diarrhea, lethargy, decresed appetite, decreased water intake and limping gait. We have had him to the veterinarian and blood work and stool Gram stain showed a left shift in his CBC . We are supporting him at home with subcutaneous fluids, Fortiflora in his food and Pepcid daily. We have had to syringe-feed him to get calories in him, otherwise he prefers to sleep. This is a significant change from the cat three weeks ago when he had his 2nd injection. We are treating a staph sinusitis from a foreign body in his sinuses. What is the half lfe of the medication? I am truly fearful for him.

    • Dr. James W. Randolph 20 October 2010 at 2:18 pm #

      Sharon, I’m not sure about the half-life but the duration of the injection in most patients is has a 10-14 day duration. Typically injections are given 14 days apart. The signs you say your kitty is demonstrating are among the reported signs that occur in some pets, though I have not seen them in our practice. Staphyloccoccal sinusitis can easily interfere with appetite, too. Most cats unable to smell will not eat. Ask your veterinarian about vapor treatments that might open his airways. Also, ask him how he feels about using metronidazole as an intestinal antiinflammatory. I have had success with it in cases such as this. Fortiflora will be very important, too. Especially with oral cephalosporins we use beneficial bacteria when reactions occur. Please keep us posted so that we may know the outcome of your kitty’s situation. Best wishes, Dr. Randolph.

  53. Foozi's mom 10 October 2010 at 7:12 pm #

    My 14 year old big boy (20 lbs) Foozi was diagnosed with diabetes and a UTI on Friday. Convenia was given to fight the UTI and I was given insulin to administer twice daily with food. Unfortunately, kitty has completely lost his appetite. Could this be a result of the Convenia? If so, how long will the side effect last? Everything I’ve read is pretty clear that insulin should not be adminsistered on an empty stomach.

    • Dr. James W. Randolph 12 October 2010 at 10:16 pm #

      Dear Foozi’s Mom: Feline diabetes is a MUCH too complicated topic to cover in a question, but it’s far more likely that Foozi isn’t eating because of his diabetes than from the Convenia. Remember that 64% of the medical information on the Internet is either wrong or outdated! ( http://www.mypetsdoctor.com/64-of-medical-information-on-the-web-is-wrong-or-outdated ). So, be careful there and get your advice from a trusted source, such as us, or your pet’s doctor. ( http://www.mypetsdoctor.com/ask-questions-of-your-pets-doctor ) Depending on what Foozi’s blood glucose and fructosamine levels are he PROBABLY needs insulin whether he eats or not. I put “probably” in all caps, bold and italics because I don’t know what his glucose and fructosamine levels are AND I don’t know what the rest of his labwork results are. In my hands Convenia has been a fabulously safe antibiotic and extremely effective. UTIs are very common in diabetics, so be sure to have the proper followup performed to ensure the infection is all gone. Write back if you have more questions, Dr. Randolph

  54. JEANETTE 5 October 2010 at 5:32 pm #

    Can Convenia be used to help respiratory problems like sinusitis? I have a cat who inhaled (possibly) ant spray and ate the ants and was having rapid breathing. He seems like he has a fever at night and also at times a serous type nasal drainage. would this be good for something like that?

    • Dr. James W. Randolph 9 October 2010 at 3:03 pm #

      Jeannette, Convenia is an antibiotic and antibiotics are for controlling infections caused by bacteria. IF your kitty has respiratory tract inflammation from chemical irritation he needs the antiinflammatory of your pet’s doctor’s choice. If your veterinarian thinks he has secondary infection after the inflammation Convenia might be a good choice. Did he have sinus inflammation prior to this episode? Chronic, recurrent sinusitis is often evidence of immune system suppression such as FeLV and FIV ( http://www.mypetsdoctor.com/feline-leukemia-virus ) and ( http://www.mypetsdoctor.com/feline-immunodeficiency-virus-fiv ). Best wishes, Dr. Randolph.

  55. D. D. 23 September 2010 at 3:25 am #

    I’ve just learned of Convenia today and suggested it to my veterinarian when the urinalysis showed white blood cells in the urine. My Veterinarian will inject Convenia in few days. Meanwhile I’m struggling giving her 1/3 capsule (estimate) of 250 mg. Amoxicillin until the appointment date. She was/is semi-feral and lost for nearly 1 1/2 months only to be found severely dehydrated, near death and 2 kg. (less than 4.5 lbs.). Evidently without food, water for that time. Therefore, it is difficult to administer further medications.
    Presently, I am trying to nurse her back to health, although renal failure is possible. Is it safe and successful for bladder/kidney inflammation in an old (over 12 yrs. min.) grossly underweight cat?

    • Dr. James W. Randolph 23 September 2010 at 5:08 pm #

      Convenia has a broad safety margin, but it sounds as if your half-wild kitty may have had a limited diagnostic workup. Is there laboratory evidence of kidney failure, or is that a working diagnosis for your pet’s doctor ( http://www.mypetsdoctor.com/tentative-or-working-diagnosis ? Even if funds or patient cooperation kept me from obtaining proper laboratory tests I would feel safe using Convenia in most patients. We wish you luck and thank you for going out on a limb for a feral cat, Dr. Randolph.

  56. Heather 23 September 2010 at 1:07 am #

    My veterinarian gave my 2.5 year old cat Convenia today to help with a fever and possible urinary infection. Blood was not visible in his urine specimen but the lab did come back with evidence of a low number of red blood cells and no cyrstals. His fever was approximately 105 degrees Fahrenheit. What is the estimated time in which I can expect to see my now-lethargic cat getting back to his normal, hungry, mischevious self? Thank you so much for your time! I feel so silly being so worried about this little guy, but he really has come to mean so much to me and my husband!

  57. Agnes G. 25 August 2010 at 10:49 am #

    Dear Dr. Randolph: My cat first exhibited signs of an injury — limping on his right foot — 4 days ago. He then became somewhat withdrawn and lethargic. The limping didn’t persist, but about a day later he vomited 3 times within a 24 hour period. His right leg and paw were still swollen but acted more normal. I took him to the veterinarian yesterday who couldn’t see any puncture wounds but did say that the leg was overall swollen and that is what caused the swollen paw. He administered him a shot of Convenia and some anti-nausea medicine. I’m to take my cat back if his condition does not improve. How quickly should the Convenia start working? His leg is still swollen. Thank you for your answer for the question.

    • Dr. James W. Randolph 25 August 2010 at 10:50 am #

      Dear Mrs. Grossman,
      I would say the correct question is not “how quickly does Convenia begin working,” because it begins to work in a matter of minutes. As soon as circulation picks up the medication and takes it to the leg, where the suspected infection is, bacteria begin being killed, IF the bacteria are susceptible to that particular antibiotic. As Convenia is a broad-spectrum antibiotic, it kills a lot of different kinds of bacteria. Rather, the question might be, “How long will it be before the swelling goes down?” That depends on how many bacteria are in the leg. The more bacteria, the longer it will take Convenia or any other antibiotic to kill ALL of them. Typically, however, (which is what you really want to know, as much of the preceding is academic) tissues infected with cat-bite bacteria and experiencing cellulitis will improve in 24-48 hours. Of course, every patient is an individual, and every bite, even on the same patient, is an individual case.
      Ask your pet’s doctor about hot-packing the area to improve circulation and speed healing, if he has not already recommended doing so. Of course, he may have a reason he doesn’t want you to do that.
      Please keep us posted on your kitty’s progress.
      Sincerely, Dr. James W. Randolph

  58. Bob Loomis 15 August 2010 at 8:41 am #

    My cat has been getting Depo Medrol injections for a reocurring skin problem. Recently she has also been getting Convenia as well. When she started on the Convenia, she has been licking herself so much that she has licked her fur off in all of the areas on her body that she can reach. She is a 2 year old Bombay in otherwise good health. Can the Convenia or the combination of Convenia and Depo Medrol be causing her skin to be dry and itchy? Thanks.

  59. Bev 6 August 2010 at 8:11 am #

    Hi Dr. Randolph: He had the Convenia injection for a severe hot spot. He’s got a sensitive stomach and cannot take oral antibiotics. This is not a coincidence because it happened once before, when he got his first shot of Convenia a couple of years ago. That time it was for an anal sac infection. He does not seem sick; he’s eating and drinking just fine. The stools still have an orange cast, but not as vivid as the first few days after the shot. My dog “Eddie” is a Borzoi and has a very sensitive system. I was worried it might be his liver, but was told by a rep from Pfizer that the drug is matabolized through the kidneys. As long as he’s not sick I’m hoping the sweet potato-colored stool is benign. Thanks for your interest. Bev

    • Dr. James W. Randolph 10 August 2010 at 11:02 am #

      Hmmmmm. That’s VERY interesting, especially since it happened once before. Thank you very much for the update, Dr. Randolph.

  60. Bev 1 August 2010 at 10:37 am #

    Convenia injections turned my dog’s stools the color of a sweet potato.
    Is this common? What causes this?

    • Dr. James W. Randolph 5 August 2010 at 9:41 pm #

      Bev, my first impression would be that it’s a coincidence, or that the disease process for which he was being treated caused the change in stool color. I haven’t seen that as a reported side effect. How long did it last before it changed back to a normal color for him?

  61. GM 14 July 2010 at 6:52 am #

    Dr. Randolph,
    I’m curious: Does CONVENIA ANTIBIOTIC make animals want to sleep more?

    • Dr. James W. Randolph 14 July 2010 at 6:13 pm #

      Not unless they are having an adverse reaction. If a patient is lethargic it is usually caused by the disease process the Convenia is being used for.

  62. GM 14 July 2010 at 6:48 am #

    Dr. Randolph, Now I have a a couple questions. Is Convenia good for any animal or just dogs and cats?
    I was told dogs and cats. Can other pets be injected with Convenia if needed?

  63. GM 14 July 2010 at 6:39 am #

    I took my cat to the veterinarian yesterday and the veterinarian injected him with Convenia.
    My cat is tired and still droopy because when I got him, he was not well to begin with. Anyhow: I Love him. :) This CONVENIA INJECTION – Seems to be working because after the injection, believe it or not, I saw a small but -weight lifted off my sholders-improvement. My cat is still droopy but keep in mind that his CONVENIA INJECTION was only done yesterday. My cat has a MUCH better LOOK about him. If I could only send a picture of before and after on this Web site, then you could see what I mean. So far,this antibiotic is a BLESSING. : ) Hope this helps. I agree with Dr. James. W. Randolph, ASK your veterinarian if CONVENIA ANTIBIOTIC INJECTION is RIGHT for your dog or cat. Have a nice day. GM

  64. Regina Lippert 12 July 2010 at 3:49 pm #

    My 20 month old Shih Tzu male had been scratching and biting himself so much that he developed scabs on his right hip and the base of his tail (“hot spots”). Since he is already on Sentinel and Frontline Plus (has been for a long time), and we did not see any fleas on him, we assumed it was allergies. I took him to my veterinarian, only to find out that he had retired, and several new young veterinarians took over his practice. The woman veterinarian who saw him treated him by shaving the areas with the scabs and cleaning them, and gave him a Convenia shot. She also gave us Hydroxyzine capsules for the itching, as needed, and a topical antibacterial spray to put on the affected areas, as well as Derma-soothe shampoo and cream rinse to ease the itching. Well, since that visit last Wednesday, my dog has not been the same. He has been acting strange, very lethargic, and is not his usual, playful self. He plops down in one spot and refuses to get up (normally he would be coming to me with his little growling bark to go outside). I have to pick him up and take him outside – once out he will only walk far enough to pee and poop, and then wants to run right back home (very unusual for him – he usually likes to walk for a while). When he gets back home, he runs inside and literally plops down in one spot, and will not move the entire day. I have only given him a total of 3 Hydroxyzine capsules, since I was afraid that might be causing him to be lethargic, and he hasn’t had one for 2 days now, and he is still very lethargic. Could it be from the Convenia? I am so upset – I want my old dog back! Will this wear off?

    • Dr. James W. Randolph 13 July 2010 at 6:29 pm #

      One of the important aspects of medical care for any species, including people, is that we don’t let problems linger and wait too long before we consult our doctors about whether something different should be done. This has been going on since last Wednesday, and that’s too long for lethargy to be allowed to persist. Several possibilities exist: 1, and I put this one first for a reason, when pets get hair removed, a protective covering is taken off the skin and that allows all kinds of sensations to be perceived that weren’t felt before. If your ShihTzu doesn’t usually do this when he’s groomed it’s not the cause, but it’s a strong consideration. 2, The skin is the largest organ in the body and if his skin is infected it could easily be causing him to feel bad. Convenia is a great drug, but it doesn’t kill every kind of infection, so IF the infection is not responding to the Convenia he might need different medication. 3, Hydroxyzine is known to cause lethargy, and it some pets it can be really dramatic. It’s possible that your ShihTzu is one of those. Now, of the three items I’ve listed, two of them require that you see your pet’s doctor for a followup visit. In addition, there are MANY other possible causes of lethargy in dogs, and just because it happened at the same time as this visit doesn’t mean there couldn’t be another problem going on. Please write back and let us know how he is. Best wishes, Dr. Randolph.

  65. Steffy 5 July 2010 at 8:56 pm #

    Hi Dr. Randolph, My late husband was a veterinarian and we surely miss him. My son had a kitty who showed up on his property in the mountains. He grew there for a few months, and then one day, his brother who was staying in his mobile home while Tay was working in Seattle, moved to a property about 8 miles away. Anyway, Max took the kitty with him and about 15 minutes after he arrived at their new rural home, kitty took off and 3 WEEKS later appeared back at Tay’s property, emaciated; a rack of bones, covered with animal bites which have turned into nasty abscesses. He made it through the night last night and Tay took him to a veterinarian who was open today, July 5. The new wonder drug was used on him, along with IV fluids, sedatives etc. It looks like he will make it. KITTY REALLY EARNED HIS REPRIEVE ON LIFE, and is a wonder he made it for three weeks with limited, if any food and water. Kitty had to go through quite a journey over several canyons, creeks and mountainous juts of rocks and cliffs. We think a wild animal got him, but he’s a trouper. Tay felt so sorry for the poor little kitty he almost used his .22 caliber rifle to take him out of his misery but couldn’t do it as it just wrenched his heart to know what the little thing had gone through for 3 weeks. Thank goodness they have this antibiotic. His veterinarian just couldn’t believe he was still alive.
    I’m writing animal stories about our adventures with my husband and I will add this one to the bunch.

    • Dr. James W. Randolph 13 July 2010 at 4:58 pm #

      Steffy, that will certainly make a great addition to your collection of stories. There are certainly some amazing stories to tell about animals making it back to their original homes. Kitty deserved to have a chance for his life after going through all that just to come back and live with Tay. Thank you for sharing, Dr. Randolph.

  66. Janine 30 June 2010 at 5:37 pm #

    Hi Dr. Randolph, Just wanted to give a quick update. The Covenia seems to have given my Annie relief in her ears and 15 days out, her sneezing and breathing are great. Her kidney issues seem to be in balance, for today, she has had about 2 good weeks, little vomiting and only missing the litter box once.
    Not sure if the Covenia helped the kidneys, but she has had good quality of life, playful, eating and sleeping of course. Quality of life is most important to me, for her now. It is and will continue to be a day by day process, but Annie has really taught me to stay in the day, and enjoy every moment with her, and really to live “ONE DAY AT A TIME”~ My Veterinarian says she is my ZEN kitty~ I hope to have her for at least a few more months but only time will tell. Thanks for your support and I will post again if anything significant develops.
    Hopeful in LA,
    Janine

  67. Stephanie 24 June 2010 at 10:52 pm #

    Hi Dr, I recently took my cat, Bear, to the veterinarian this past Tuesday because I noticed there was blood in his urine. They gave him a shot of Convenia but he is still showing blood in the urine. He is not crying out as if he is in pain, and is still going regularly, even if it’s not a whole lot, but on two occasions he was lying down and urinated a tiny bit while just lying there. He has been given oral antibiotics for this before, once last October and previously in Nov. ’06. I believe I caused the one in Oct. of last year, by changing his food from a food meant for Urinary Tract health (Purina One). Since then, he’s been on a diet of Wellness dry cat food and once or twice a week, the Purina Urinary Tract health wet food – because he loves it so much! I was recently getting away from feeding him this Purina wet food, because I thought the Wellness would take care of his issue. Now it seems I have caused him to be sick again! What exactly is the best food for cats that are prone to this issue? Once I know, I will never ever switch food again! Also, we are taking him back next week for a urinalysis to confirm his diagnosis. But I am hoping the blood in the urine and his urge to go all the time, and outside the litter box will resolve itself sooner. Do you think he will be better tomorrow or should I take him back to the veterinarian before the weekend? Thanks so much for your website. Just reading the comments has helped!

  68. Janine 15 June 2010 at 8:24 pm #

    Thank you Dr Randolph. As for Annie’s ears, because of her chronic respiratory/herpes, and recent allergy season, she has been sneezing excessively and has a tremedous amount of phlegm. Not pretty, but a fact of life with a cat like my Annie! When I asked if the chronic renal failure had anything to do with her hearing, my veterinarian said it might, might be from her chronic sinus issues. She looked in to Annie’s ears with a scope and found the ear drums to be “thick” and she said could be a number of things, but probably associated with the sinuses. Because she also sqeaked a bit when the doc tried to look in, (she is normally so stoic) clearly it was painful. The doc said since she tolerated it well once before, and it did give her about 3-4 wks of relief from the sneezing, I said ok. Do you have any additional thoughts we could explore? Thank you in advance. I appreciate your prompt response. Janine

    • Dr. James W. Randolph 17 June 2010 at 1:19 pm #

      I certainly agree that with thickened tympanic membranes, the sinus issue on “the other side” could be a factor. As eardrums thicken they become less pliable and thus less responsive to sound waves hitting them. I completely agree that it’s worth a try. Keep us posted on how Annie responds, please. Our best, Dr. Randolph.

  69. Janine 15 June 2010 at 12:06 pm #

    My kitty, Annie 15 1/2 yrs old was diagnosed with Chronic Renal Failure about 5 wks ago. My veterinarian gave her Famotidine (Pepcid), for nausea, daily, Epogen every other day and 100cc of subcutaneous fluids. I am happy to say we took her off of Epogen last night but will continue with subcutaneous fluids and Pepcid. Annie also has had asthma/allergies for the past 10+years. So, because of the flareup of her allergies, she has been phlegm-filled and sneezing lately. I noticed her shaking her ears and told the veterinarian that she wasn’t hearing as well. The veterinarian chose a Convenia injection as a course of action, since she tolerated it well once before. My question, in treating her clearly-hurting ears, will it take to notice some improvement? Is is like human antibiotics, 2-3 days? It has been 14 hours. Thank you in advance.

    • Dr. James W. Randolph 15 June 2010 at 7:41 pm #

      You will find this post informative regarding how we choose antibiotics, the specifics of which are mostly independent of species (human vs. dog or cat). In Chronic Renal Failure (CRF) Pepcid is used for nausea, but more importantly to control ulcers and other forms of gastric irritation that occur secondary to changes in the disease process. Subcutaneous fluid therapy should continue for the life of your kitty, and check with your pet’s doctor about whether the quantity should be adjusted from time to time. Epogen must be used judiciously because, for a variety of reasons, the body can cease to respond to it at some point. Epogen should also be used with careful guidance from your veterinarian. Please tell me more about your kitty’s ears so that I can address them specifically. Standing by, Dr. Randolph.

  70. Erin 10 June 2010 at 8:57 am #

    My 3-year old Siamese was diagnosed with a UTI on Monday and was given Convenia. The urinary symptoms have improved (much less frequent trips to the littler box to urinate), and he’s eating and drinking well. However, he seems much more lethargic than normal and hasn’t had a bowel movement since Tuesday morning. I have a call into the veterinarian, but thought I’d check with you as well. Is it just a stress issue, or is lethargy a side effect of the medication?

    • Dr. James W. Randolph 11 June 2010 at 9:42 am #

      Erin, I would assume that the lethargy is associated with the disease process, because we don’t usually see lethargy with antibiotic administration. Of course, we don’t administer antibiotics to well patients, we give them to sick patients, many of whom are already lethargic. Certainly if the lethargy persists I would check in with your pet’s doctor to get his evaluation. Best wishes, Dr. Randolph.

  71. Linda 7 May 2010 at 1:57 pm #

    Are there situations where this injection is not sufficient as an antibiotic? My Dad’s cat had one for a gum infection. That was 3 weeks ago. Today, she has a fever. Her gums seem okay, but I wonder if somehow either that one shot was not enough or that she needs another type of antibiotic. Drinking water alone seemed to bring the fever down. Could this fever be related to the original infection?

    • Dr. James W. Randolph 7 May 2010 at 6:16 pm #

      Linda, you answered your own first question when you said, “needs another type of antibiotic.” This post explains why there are so many antibiotics on the market: http://www.mypetsdoctor.com/stronger-antibiotics. How high was her fever? Write me back and let me know because one of the factors we use to make decisions about patients is to look at the actual number. We will await your reply. Dr. Randolph.

  72. Keith Johnson 5 May 2010 at 9:13 am #

    On April 16th, I took in my sixteen year old indoor female cat (Kola) for the annual Rabies and FVRCP vaccinations required by Cook County of Illinois. My cat had been treated for three years for hyperthyroidism with an oral medication. The veterinarian noted weight loss from the previous visit six months prior and recommended a special kidney diet. Blood was drawn at this time. A few days after this visit, Kola started urinating more frequently and more times outside of the litter box. She had received Convenia the previous year for a similar occurrence and it worked well. I returned to the veterinarian and Convenia was administered. After this visit, Kola progressively got weaker and weaker. Another visit to the office was scheduled. The lab work was back and all results were either in the normal range or just moving beyond the limits. The veterinarian could only speculate on the cause for the weight loss and weakness.
    Over the weekend, Kola weakened to the point where she could only lie on her side. She would still take food and water through a syringe. Yesterday, she was virtually limp and I had her put to sleep.
    Was the combination of Rabies, FVRCP, and Convenia injections too close in time? (Four days apart). Kola’s decline was so rapid. I’m heart broken over her loss and whether I did not give her the proper care.

    • Dr. James W. Randolph 7 May 2010 at 5:46 pm #

      Keith we are SO sorry about the loss of your Kola. I know you are heartbroken. If you are a regular reader you know that we, too, have an elderly cat, Martha, who has some age-related problems, and we can certainly relate to how attached we are to a pet we’ve had for that long. Without the laboratory test results and physical examination notes from the medical record I could only speculate as to the cause of death, but I doubt that the injection process was the cause. I won’t say it didn’t play a part, as cats in this age group can be put out of balance for any number of reasons. Our sympathies on your loss, Dr. Randolph.

  73. Therese 17 April 2010 at 4:39 pm #

    I have a cat who is about 10 years old. She started having allergy type symptoms with small bumps all over her body about a year ago. They itch and are sometimes painful. Her ears get a little crusty. The only place the bumps do not appear is her tail. She pulls her fur out and leaves it all over the house. Sometimes the skin end of the fur has a little crusty black hard piece at the end of the shaft area. We have taken her to the veterinarian for the 4th time in a year. We have tried a special shampoo (that’s right, try giving YOUR cat a bath!), switching food, cortisone injections (which clear it up for a month and then it comes back) Her appetite is fine but I know she is uncomfortable. We have 4 other cats and they do not have this problem so we know it does not cross-contaminate. She recently received a Convenia injection. We are ready to give her low-dose prednisone daily as that seems to be the only thing that works, but I know this can have secondary effects. Any idea of what’s going on? Help!

    • Dr. James W. Randolph 19 April 2010 at 4:35 pm #

      Therese, let’s start with the basics. What diagnosis did your veterinarian give you?

  74. Tonya 9 April 2010 at 9:49 pm #

    Dear Dr. Randolph, my cat had an adverse reaction to azithromycin and experienced swollen paws. Once the swelling went down the pads on his feet became hard. Some skin on his legs has fallen off and scabbed up. The wounds are beginning to heal but the pads are still very hard on his front paws. His right paw the entire paw has hardened like a rock. He is having pain with walking. He has received a couple of Convenia injections and with Epsom salt baths some of the hard skin has come off but his right paw is still extremely hard. Are we on the right course of action for treatment?

    • Dr. James W. Randolph 19 April 2010 at 5:46 pm #

      Tonya, reactions that result in vascular (blood vessel) damage often cause death of tissue such as you describe. Pets, people, farm animals, all are subject to some really disastrous wounds when this type of damage occurs. Your may concern is to maintain antibiotic therapy until healing is finished (continued Convenia injections are fine if he is tolerating them) and you may wish to ask your veterinarian about an emollient to help soften the skin and crusts. Gentle massage can help, as can whirlpool baths IF your veterinarian approves them. Please keep us updated about your baby, this is a heartbreaking story.

  75. Kendal 9 April 2010 at 5:19 pm #

    Dr. Randolph, he is feeling much better today and has stopped trembling. The wound looks better too. I definitely agree that he was just uncomfortable. He has also been sleeping a lot but I think that is because his body is fighting off the infection. Thank you again for your help.

    • Dr. James W. Randolph 13 April 2010 at 12:01 pm #

      I, and all of our readers, are delighted that your kitty is feeling better and the wound is healing. Thank you for the update.

  76. esteban aldrin 8 April 2010 at 9:42 pm #

    Is a Convenia injection good for eye problems or irritation?

    • Dr. James W. Randolph 9 April 2010 at 3:54 pm #

      As with any medical condition, whether a certain medication is good or bad for a certain condition depends on the diagnosis and the appropriateness of the medication for that particular diagnosis. That said, I can’t imagine using Convenia alone for an eye condition other than uveitis. Please write back with more information.

  77. Kendal 8 April 2010 at 12:24 am #

    Dear Dr. Randolph,
    My kitty escaped from my house 4 nights ago, thankfully he came back the next morning. I checked him over to make sure he didn’t have any bite marks, wounds, etc. While checking I noticed a small lump on his right side, I wasn’t too alarmed and just figured to keep an eye on it. Well, when I came home from work yesterday, the small lump on his side had came open. It looked horrible. I immediately took him to my veterinarian. She said that it was bite from either a cat, raccoon, or rodent (most likely a cat). She prescribed Convenia and told me to flush the wound 2 times a day with chlorhexidine solution. I know my kitty is in immense pain, but he has been trembling ever since I have brought him home and has been acting very skittish, he is normally a calm kitty and actually enjoys car rides. I wonder if his trembling and behavior is a side effect of the shot? I have a follow up appointment in 2 weeks but I want to make sure it’s just my kittie’s nervousness and not a side effect of the antibiotic. Thank you in advance for you help.

    • Dr. James W. Randolph 9 April 2010 at 4:01 pm #

      Kendal, the greatest likelihood is that your kitty is trembling because he is uncomfortable. Of course, there is always the possibility of internal damage that may be causing complications. This is one of those situations where the veterinarian attending the patient will need to make the judgment call whether to dispense pain medication or see the patient for a followup. Please keep us posted.

  78. Ginger 2 April 2010 at 12:33 am #

    For Mindy from Ginger: Bless you for your dedication to your kitty. Although right now it’s so hard, time will be your friend. You will recall many joyous times you had with your kitty. The love of a pet is so pure, both ways, that you will never have regrets or guilt. Pets don’t let you down like people do. That has been my experience. My Midnight has been gone just over a year and I am at peace with his passing.

    • Dr. James W. Randolph 5 April 2010 at 3:32 pm #

      And God bless you, Ginger, for reaching out to your fellow pet lover who is hurting.

  79. Sally 31 March 2010 at 6:06 am #

    My cat had a shot of Convenia for dermatitis. She had not been diagnosed with anemia before but quickly developed anemia within a couple of days and had to be put to sleep 7 days after the injection because she was so weak. She also seemed comatosed after the first couple of hours of the shot and had tremors. She developed anorexia so had to be force-fed with a syringe. In my opinion Convenia contributed to her death and should be used with extreme caution. I believe it is a useful antibiotic for some people who can’t pill their pet. I knew nothing about this new “wonder drug “when I took my cat for a check up and the veterinarian did not inform me beforehand only once it was already in the system.

    • Dr. James W. Randolph 31 March 2010 at 11:37 am #

      Dear Marie,
      What a tremendously sad story.
      I am so sorry you have lost your kitty.
      While her death occurred in temporal conjunction with the Convenia injection, I seriously doubt that Convenia was the cause, although it is not impossible.
      There are many, many, many possible causes for anemia that I would put on my differential diagnosis list before Convenia.
      I would encourage you to file an adverse-reaction report with the manufacturer: http://www.pfizerah.co.uk/sites/sante-animale/UK-English/pages/contactez-nous.aspx
      I know that veterinary practice is probably somewhat different in England compared to United States practices, but the patients are the same, and the hurt we feel when we lose them is the same.
      Please accept our sympathy for your loss, Dr. Randolph.

  80. mindy 28 March 2010 at 5:04 pm #

    Hi. This will be my final update. I had to put my baby girl down today. She was just too weak. My heart is breaking into a million pieces. I think her sister senses she is gone. I hope she does ok. I will have my baby’s ashes by Tuesday or Wednesday. That’s going to be hard, too. I just don’t know how to continue without her. But she went peacefully. I just hope she wasn’t mad at me. I couldn’t handle knowing her last thoughts while looking in my eyes were of her begging me not to do that to her. I do appreciate your advice and information these past few weeks. It really helped.

    • Dr. James W. Randolph 29 March 2010 at 12:04 pm #

      Mindy, there is not a dry eye in MyPetsDoctor.com-land right now. We all know how you feel and understand your hurt. DO NOT worry about her being mad at you, you didn’t do this TO her, you did it FOR her. There was no reason for her to continue to suffer, knowing she was not going to get better. When the prognosis is poor, that is the right thing to do. You may find this post comforting. I wrote it after losing my precious Sally. http://www.mypetsdoctor.com/pet-loss-and-grieiving-for-pets

  81. mindy 24 March 2010 at 3:27 pm #

    Hi. I was back to the veterinarian today for a checkup and wanted to give you an update.
    It’s really just a day by day thing. Just need to make sure she is eating and keeping it down. I think giving her the subcutaneous fluids helped. She hardly made a sound on the way to the veterinarian, but she was mostly definitely vocal on the way home lol
    The doctor gave her an enema and she had a nice poop. Wasn’t really a lot in her i don’t think, but hopefully that was all she needed to feel better. She was throwing up so much yesterday and last night that I was terrifed to go to the appoinment today. I’ll be taking her in once a week to have IV of fluids which will help keep her hydrated and eating.
    She hardly ate anything at all last night but when I brought her home she finally ate and had a little sleep.
    There is definitely a lot of weight off my shoulders today. The only thing is that the injection she got last Saturday stays in her system for 2 weeks, which means this Saturday will be her last day. So it’s really going to be a waiting game after that…but the doctor said I can give her a little tiny bit of Pepcid which would help with her upset stomach if she still urges to vomit.
    To make matters worse I came home yesterday and her sister was sick. Constipated to be exact…so I was cleaning up vomit all day yesterday when I came home. How lovely for me lol
    So, needless to say there was a big relief when I came home this afternoon. Just gotta keep my eye on her.

  82. mindy 20 March 2010 at 5:19 am #

    Wanted to provide you with an update. Had her to the veterinarian yesterday and every test imaginable was completed. Unfortunately it’s not good news. She has a mass on her bladder that is causing her to frequent the litterbox and the reason there is blood appearing after she urinates. She has lost about 75% of the function of one of her kidneys and all I can do at this point is keep her comfortable and make sure she still eats. I probably don’t have much longer with her. I take her back for a check up on Wednesday and have some more fluids put in her. All I can do at this point is try to help her the best I can at home but I think her body is slowly shutting down. She spent most of the night last night in the closet on a blanket. Could have either been because she had a rough day at the veterinarian or it’s her way of saying it’s time to go. My heart just isn’t ready for that yet, but I won’t let her suffer either. Thanks for all the help and advice over the last couple of days

    • Dr. James W. Randolph 23 March 2010 at 12:55 pm #

      What an incredible heartbreak, Mindy. We are SO sorry to hear that your kitty has such serious problems. Please let us know if we can help in any way.
      In sympathy,
      Dr. Randolph

  83. mindy 17 March 2010 at 11:32 am #

    Thank you for the reply. I did want to add another question. Would it be beneficial and advisable to get her on some special food for urinary tract health? Would this help to alleviate any trouble she is having with her urine?

  84. mindy 16 March 2010 at 5:40 pm #

    My cat had this shot last June and it worked WONDERS..she was urinating all over the place and I never realized it until I caught her with my own eyes. Well, a few days ago, she was back to the same thing….but this time it seemed a bit worse….she was throwing up…meowing all over the place (in pain), passing very little urine, drinking a lot…took her to the veterinarian on Saturday..there was blood and white blood cells in her urine…veterinarian gave her the shot again…she seems to be doing much better BUT, she is still passing little urine, and is still frequenting the litter box more than she should. Am I worrying for nothing and just need to give another day or so for the injection to be in effect? Or could there still be an issue?

    • Dr. James W. Randolph 17 March 2010 at 10:44 am #

      Mindy, there are myriad reasons for your kitty to have difficulty with the urinary tract. In cases like yours, where small amounts of urine have been passed, we sometimes have to begin symptomatic therapy on the assumption that there is infection, when, in fact, there could be causes of inflammation unrelated to infection or infection that is complicated by other factors. You have inspired me to write a piece about this very complicated topic, and I anticipate posting it this Friday. For now, give your kitty another day or two, but if she isn’t doing better soon she will certainly need a followup visit to your pet’s doctor.

  85. shari 12 February 2010 at 12:15 am #

    Just thought of one more question. another veterinarian has theorized that feeding cats the diet that is natural for them – lots of meat, could help a lot of felines feel a whole lot better. it makes sense that cats’ bodies evolved on a high-protein diet and that us inadvertently giving them far too much carbs is causing our fluff-balls all sorts of needless suffering. Just like how us humans are eating too many carbs, too, and suffering for it with diabetes and etc. Thanks for your thoughtful replies.

    • Dr. James W. Randolph 25 February 2010 at 5:18 pm #

      There is a growing movement in the direction you cite, and it has merit. Indeed, I am watching the outcome closely. All cat owners should.

  86. shari 12 February 2010 at 12:10 am #

    Would it be a problem giving Fluffy her beloved daily dose of plain yogurt while this shot is doing its job? I’ve heard about problems with some antibiotics and all the healthy bacteria in yogurt. Thanks.

  87. Jennifer 30 January 2010 at 6:04 pm #

    I recently got a Chorkie puppy who had severe itching. He was losing a lot of hair and the second day I had him the doctor gave him the shot Convenia. He wasn’t moving or eating much but I thought maybe this was typical of him since I hadn’t been his owner for long. Three days later he could not walk or even stand up. His legs were wobbly and his eyes were “lost.” He had to get 2 blood glucose sticks as well as Karo and the veterinarian told me he probably wouldn’t make it. I had to feed him every few hours and also give him a nutritional supplement. Finally after about ten days he started acting like a puppy again. Now over a month later he has scaly stinky skin and had previously been diagnosed with sarcoptic mange. I am going to take him to the veterinarian again but am afraid they are going to administer Convenia again.

    • Dr. James W. Randolph 30 January 2010 at 7:02 pm #

      The good news, Jennifer, is that it wasn’t the Convenia that made him hypoglycemic. The most likely cause is an inherited predisposition from his Chihuahua heritage. Hypoglycemia is very common in that breed. Yorkie puppies are also predisposed to hypoglycemia, as well as shunts in their livers, which can cause severe illness. The other good news is that Scabies, or sarcoptic mange, in dogs is usually easy to treat. In resistant cases there are alternative medications that can be used. Scaly and stinky WITHOUT itchiness probably isn’t Scabies, but still needs investigation and treatment, so don’t delay taking him to the doctor. Scabies is sometimes transmitted to people, so be sure to let your physician know your puppy has Scabies if you become itchy.

  88. Azza 29 January 2010 at 7:38 am #

    My 5 year old male cat suffers from Urinary Tract Infection. It recurred 3 times in one year. In August 2009 he was diagnosed with UTI and he got medication and antibiotics, then 2 weeks later it recurred. I took him back to the veterinarian and she gave shots and antibiotics and he was on a special diet (Royal Canin) for around four months from August to November and I noticed that he lost weight so I switched back to commercial pet food: Whiskas and Purina. Yesterday I saw him straining and something white is coming out with tiny drops of urine. I think UTI recurred and I will take him to the veterinarian tomorrow as it’s the weekend now and he is closed. I am so worried about my cat especially we don’t have specialist veterinarians in my country (I live in the UAE). All of the veterinarians are telling me to just feed him Royal Canin but its not working out. Please help my cat :(

    • Dr. James W. Randolph 30 January 2010 at 6:35 pm #

      Azza, it sounds like to me that the Royal Canin was doing its job, and that the problem only relapsed after you changed foods. For those cats who create struvite crystals in the urine by concentrating magnesium, ammonium and phosphate ions in the urine, I have seen a SINGLE MEAL of the wrong food create a relapse. If he is losing weight on Royal Canin but maintains a healthy weight on other foods, ask your pet’s doctor whether he can just eat MORE of the Royal Canin. That should solve the weight issue AND the urinary tract problem. IF there are future problems with the urinary tract, please ask your veterinarian to culture the urine to determine whether there ACTUALLY IS infection, or whether the bladder wall is inflamed from crystals, or possibly idiopathic cystitis.

  89. Carolyn 28 January 2010 at 9:27 pm #

    Dr. Randolph, Exactly one month ago I played with a sick kitten with distemper. I wasn’t worried because my cat was vaccinated 11 months ago. My 3 year old cat started hacking yesterday, but nothing came up. Didn’t think much of it, since she vomits hairballs about once a month. Today she showed other symptoms such as not eating or drinking, acting sleepy, slightly closing one eye, walking around very slowly, but otherwise staying in one spot. I fed her water and gravy from soft food through a dropper 2x today. Could she have contracted distemper or another disease from my clothing?

    • Dr. James W. Randolph 30 January 2010 at 6:18 pm #

      Carolyn, cats don’t get distemper, it is a disease of canids (dogs, wolves, coyotes, racoons get it, too), but what is sometimes mistakenly called “feline distemper” is actually Panleukopenia. That doesn’t sound like what your cat has. It is easy for fomites (objects can transmit a disease without modifying it or otherwise playing a part in its progress), such as clothing or your unwashed hands to transmit any of the several upper respiratory diseases cats get. Because some of these can be serious you should obtain an appointment first thing Monday so that your cat can receive a proper diagnosis and the correct treatment. Remember, too, that there are diseases we cannot vaccinate against, so your kitty is not immune to every disease there is, only the ones we vaccinate against and the ones she gets “community” immunity to.

  90. Jan 26 January 2010 at 7:27 am #

    My 3 year old cat has recurring Urinary Tract Infections. Two days ago, she starting getting ill–lethargic, not eating or drinking, not urinating–so I took her to our veterinarian yesterday. Her temperature was 105; the culture results showed she had a bladder infection, and the veterinarian gave her a Covenia injection, a cortcosteriod injection, and injected water under her skin. My questions are: Since it appears that we never quite get rid of the UTIs (since they recurr within a few weeks), should I take her back for another culture? If so, how many days after the inital visit and injections should I get another culture? Should I ask the veterinarian to start an oral antibiotic regimen after the 10 days of Convenia coverage? My cat will take pills. It’s been 24 hours since the Convenia shot, and she is not noticeably better. Two weeks ago, when she was given oral antibiotics (Clavamox 62.5 mg.) for a UTI with 105.9 temp, she was nearly back to her old self within 24 hours. Thank you for your help.

    • Dr. James W. Randolph 28 January 2010 at 11:10 am #

      There are several things that concern me about your kitty’s recurring UTIs.:
      1. Whenever UTIs recur we become concerned that there is an underlying cause, such as bladder stones (these are not always palpable, sometimes an X-ray, or even a double-contrast X-ray, or cystoscopy are required), bladder wall defects, such as persistent urachus (a defect from birth) or even tumors of the bladder.
      2. How long is she taking medication? If I use Convenia for a urinary tract infection I typically repeat it in 2 weeks, giving the patient a full month of antibiotic therapy.
      3. If using oral therapy I like to give a minimum of 3 weeks of therapy.
      4. That your pet’s doctor is culturing the urine means that he knows which antibiotics will work best. It’s possible that she just needs to take the right antibiotic longer. For recurring problems I’m not afraid to use an antibiotic for a couple of months, if it’s indicated. Sometimes an antibiotic is effective in the laboratory, but not in the body. Use of a different antibiotic from the list, for an adequate time period, may help.
      5. Other underlying problems can include not cleaning the litterbox frequently enough (twice or more daily is NOT too much!), folds around the vulva that predispose to holding infection, inability to hold a squatting position and keep vulva from contacting the litter (unlikely in a 3-year-old).
      If your veterinarian is unable to perform the tests listed in (1), he can refer you to a specialty practice where those can be done. For example, few general practitioners own a cystoscope.
      6. Few feline patients spike fevers so high with uncomplicated lower urinary tract infections. Her kidneys may be involved. You need to take her temperature at home a few times with her well, and the next time she’s sick, before taking her to the doctor. Some patients raise their body temperatures from the excitement of going to the doctor.
      7. What are the results of her CBC and Chemistry Profile?

      These are major points, there are some less-likely possibilities, but it provides you with a strong starting point.
      Please do keep us updated on your kitty and her response to therapy. We will be eager to learn how she does.
      Best wishes,
      Dr. Randolph

  91. Karen 25 January 2010 at 1:27 pm #

    My veterinarian wants to draw blood yearly (CBC/Chem 11) from my indoor cats, ages 1 to 1 1/2 years old. Is this necessary?

    • Dr. James W. Randolph 28 January 2010 at 11:24 am #

      Dear Karen,
      The answer to this question really comes down to what level of care you want for your pets and what you can afford. I commend your pet’s doctor for wanting to do what’s best. Are your pets at high risk? Probably not. Are they of breeds that might have a predisposition to certain problems, such as Persians with a genetic tendency to PKD? If there are predispositions your veterinarian should be able to explain those to you. At some point, probably around 5-7 years of age, he will want to add a thyroid test to the panel, as cats in this age group may begin to develop overactivity in the thyroid glands.
      What percentage of cats will be helped by this program? Probably a small percentage. BUT! if it’s your cat, or your favorite cat, and he detects abnormalities early, you sure will be grateful for the testing. As I always say, if we knew the test results, we wouldn’t need to run the tests, but we can’t tell by looking which cats, or dogs, are harboring subclinical health problems.
      Many, many pets whose problems are caught early will benefit in terms of degree of success of treatment and longevity.
      Bottom line? If you can afford it, by all means do the tests. If you can’t, save up for next year’s tests, and plan ahead to have the funds available for each successive year.
      Thank you for the question and for your readership of MyPetsDoctor.com,
      Dr. James Randolph

  92. Linda Kliphan 10 January 2010 at 1:52 pm #

    My 9 year old cat, Lotus, has suffered from chronic upper respiratory infections for years. She has been treated with several different medications, some of which caused her to vomit. When my veterinarian finally found one that she could tolerate (Orbax), it helped while she was on the medication, but the symptoms (thick yellow discharge from her nose, sneezing, gulping and struggling to breathe) came right back right after she had finished the medication. I recently heard from a friend about Convenia. Lotus was given the injection 2 weeks ago, and is still doing fine. Her nasal symptoms are completely cleared up and she’s gained a little weight which she needed. This treatment has been a Godsend after years of seeing my little girl suffering and not being able to help her. I realize that she will probably have to have these shots periodically, but to find something that helps her is such a relief.

    • Dr. James W. Randolph 16 January 2010 at 9:02 pm #

      It is understandable that Lotus is still doing well 14 days after her Convenia injection because it has a 14-day duration of effectiveness. The real test will be how well she does after the medication is no longer in her system. What diagnostic tests has Lotus had? Some cats with chronic problems like this are infected with Feline Leukemia Virus and/or Feline Immunodeficiency Virus (you may search for each of these terms on any page of MyPetsDoctor.com for articles on the topics). Some have polyps or other obstructions to sinus drainage flow. Foreign bodies, such as blades of grass or other objects can cause chronic reactions such as you have described. Such problems may be easily diagnosed by use of a tiny scope passed into the nasal passages of an anesthetized patient. Commonly this is done at a referral center your pet’s doctor can send you to. In cases of chronic viral rhinotracheitis virus (which we will have a post on in the next few days to weeks) some patients improve with immune system boosters such as Enisyl. Best wishes, Dr. Randolph.

  93. Pam 3 January 2010 at 1:30 am #

    My 13 year old dog has been urinating constantly both inside and outside the house. He takes a very long time to urinate and he seems to be straining a lot. I took him to the veterinarian on Tuesday and he received a Convenia injection. It has been 4 days but there seems to be no signs of improvement. How long does it take to see any improvements?

    • Dr. James W. Randolph 5 January 2010 at 6:25 pm #

      Pam, let’s start with more information: 1) Did your dog have a urinalysis and, if so, were there bacteria seen? 2) Was his prostate palpated and, if so, was it normal or abnormal in both size and shape? If it was abnormal, I need to know all the ways it was abnormal. If you don’t know the answers to these questions your veterinarian can supply them.

  94. Chris 31 December 2009 at 10:42 pm #

    Hi Dr. Randolph,
    My cat Ernie went to the veterinarian today because his paw pad appeared to be infected. The veterinarian said it appeared to be the result of a cat bite from his brother (the only two animals in my house). He did try to get some pus out of it but not much came out. He received an injection of Covenia. How long until I should expect results on his paw pad? On a side note Ernie appears to be REAL tired tonight, is that a natural reaction? I suppose that long with the stress of actually going to the veterinarian didn’t help either. I just noticed him eating and he used the litter box about an hour ago, just not quite his normal self.

    • Dr. James W. Randolph 1 January 2010 at 5:50 pm #

      Ernie is a sick kitty, so we wouldn’t expect him to be himself for a few days. How long until he is “himself” or “normal” again depends on the type of bacteria in the wound, his body’s immune system reponse to the infection and how long the infection was there before treatment began. Did the doctor instruct you to flush the wound? If not you should at least press gently on the area twice daily and try to get out any pus that you can. Hotpacking the area would help bring healing circulation in, too. If Ernie did not have a Feline Immunodeficiency Virus test, he should.

  95. Diane Campos 28 December 2009 at 9:02 pm #

    My cat Howie (domestic long hair) seems to get upper respitory infections alot. My veterinarian treats him with rounds of Amoxcicillin and Vyralis (sp)?. The symptoms always seem to go away and come back after a few months. Now he is on shot of Convenia and the amoxcicillin. He lost his appetite and had to have fluids administered. I just do not understand why he keeps getting relapses after all the treatments I give him with the immunity boosting gel. He is an indoor cat only. Any suggestions?

    • Dr. James W. Randolph 29 December 2009 at 5:02 pm #

      Howie probably has a chronic infection with Rhinotracheitis virus. As it is a herpesvirus and the body’s immune system never completely clears it, infected cats are predisposed to relapses. You may also want to have investigated the possibility of foreign bodies or growths in the nasal passages. Convenia and Amoxicillin are commonly-used antibiotics for this, but there are some high-powered antibiotics your pet’s doctor might also choose to use. They can be pricey, but may give you a longer time period between relapses. Of course, we must always keep in mind that antibiotics kill bacteria, not viruses, so IF he has chronic Rhinotracheitis he will always be predisposed to relapses. I have assumed that Howie has been recently tested for FeLV and FIV (you can search for these on MyPetsDoctor.com for in-depth explanations) and tests must always be paired: two tests that agree, positive OR negative, two months apart. Cats infected with either one or both of these immunosuppressive diseases will be predisposed to URTIs as well as other chronic, relapsing health problems.

  96. Anny 4 December 2009 at 7:41 pm #

    Hi,Dr.Randolph,
    My cat, Money, is about 4.5 years old. Few weeks ago, after she came out from the litter box, I saw some light brown liquid on the floor and it had very bad smell, very stinky. I took her to the veterinarian and the veterinarian said she “might” have a lower urinary tract infection and gave her one injection of Convenia. The veterinarian told me if she didn’t get any better within 10 days, then I would need to take her back for urinalysis. It’s been 3 weeks since she was given the injection. This morning I found few drops of brown liquid (a little bad smell) on the floor after she used the litter box. I don’t know if Convenia worked 3 weeks ago but now she has the infection again? Should I take her back for another Convenia? Is urinalysis necessary before antibiotics or treatments are administered?
    I add a lot of water in her cans, so she drinks a lot of water. She urinates more often than another 2 cats I have with the size of urine clumps between golf ball and baseball size. Is this normal? The amount of her urine each time is not much, can it be because she urinates more often?
    Thank you very much. I am very worried.

  97. Deanna Attee 28 November 2009 at 3:59 pm #

    Hi Dr. Randolph. I have come across your website while doing research on Convenia. My cat, Wiggy, was treated for blocked urinary tract (struvites) in Dec. ’08. I refused the Convenia because it’s new and long term side effects unknown (this was pre-blockage). A few hours later he was admitted because he became totally blocked. He was given Convenia (against my wishes) during his course of treatment as he is too aggressive at the vet to do oral administration (I would have done it). But anyway, it is nearly a year later and my cat is somewhat better since the spring but overall, has not improved past a certain point. His bowels have never recovered from the antibiotics (he had a round of Clavamox in April as his pH became elevated and we were afraid UTI was recurring). While he does not have consistent diarrhea, his stool is mostly loose, sometimes liquid, occasionally solid. He is somewhat weakended in his motor skills – jumping calculation and such and his hind end seems a little stiff (and also it seems when he sits, he does not sit all the way down – bowel related?) My main concern is his weight. He has remained 1 to 1/2 lbs. underweight since June. He is on probiotics, essential fatty acids, milk thistle (for slightly elevated liver panel) and will be getting digestive enzymes starting today. He is on food prescribed by my vet (Iams Intestinal Low Residue – which I consider sub-standard) as this seems all he can tolerate (Solid Gold, what my other cat eats, gave him diarrhea). He also gets canned food (Wellness) – which though he needs the moisture, I think is partially responsible for keeping his stool soft as when he was on dry only, his stool was solid much more often). He eats well most days. I have gotten the cats a water bubbler but they still prefer the tub. As of Aug. ’09 his ALT was 286 U/L and T4 = 2.0. I have also just discovered (today) in reviewing Wiggy’s records, that in December, when he was having his catheter removed, his heart stopped twice and he had to be intubated and given CPR. I was never told about this and am highly upset to discover this via notes. The notes prior to cardiac arrest are as follows: “Tanlad down w/ Iso. [??] Removed sutures and u. cath. Rx: Buprenex 0.2 cc IM. Started to admin S0F when cat’s heart stopped.” The first line I do not understand. Also unclear as to why my cat’s heart stopped (this was not his first exposure to Buprenex).
    I am really at my wits end with my vet. I live in a small town, there are no holistic veterinarians here and all my vet wants to do is give my cat more drugs or is generally lax about follow up. In general, she seems to have no clue what is going on. Taking my cat to the veterinarian is highly stressful for him – more so than is usual. Just getting his blood is terribly stressful. He is a fighter. I know he likely needs more bloodwork.
    Any direction you can shed would be most appreciated. I am willing to give my cat drugs if they are helpful, I am not willing to medicate him needlessly and with shotgun diagnosis. I just want him to be well, not do things that make him sicker. I am willing to pay for phone consultation if you think it would be more condusive. Thanks for putting your time into this website.

  98. Jennifer Stoops 27 November 2009 at 10:17 pm #

    Dr. Randolph:
    My nine year old cat Ella had an injection of Convenia on 11-24-09 I took her to the veterinarian because she was sneezing a lot. No temperature and was eating normally. I have another cat Louie who is 4 years old. They like to go outside on a leash when it is nice which in South Carolina is a lot of the time. We have been away recently so they haven’t been out as much till last week. Ella also got a Depo Medrol injection on the same day as the Convenia. She seemed fine till today and the sneezing is back again. Our vet is out till Monday Nov. 30. She is eating and using the litter box. Should we see results from the meds by now? Last January Ella had urinary infection treatment with antibiotics and is on Hill’s Prescription Diet C/D multicare food for cats now. Also she gets Dasuquin which is supposed to help with decreasing crystals which she had on urinalysis. I am due to go away again and a close friend pet-sits for me. The chest is clear. Any thoughts here would be appreciated.

    Thanks,
    Jennifer A. Stoops

  99. peggy peak 19 November 2009 at 9:05 pm #

    My 9 year old Lab has severe skin problems, sores and itching. Would this drug help him?
    Thank you, Peggy.

  100. susan mccoy 17 November 2009 at 3:06 am #

    My cat was diagnosed with a UTI today and given a Convenia Injection. How long should it take to notice improvement?
    Appreciate your advice,
    Susan

    • Dr. James W. Randolph 17 November 2009 at 10:25 am #

      The length of time to improvement depends on the initial presenting signs and the urinalysis findings. If he initially presented with straining to urinate and blood in the urine it could be several days before those aspects are resolved. If the bacteria were round (cocci) as opposed to rod-shaped (bacilli), we woud usually expect faster improvement. We hope your kitty is doing better real soon. Keep us advised, Dr. Randolph

  101. melisa cortez 15 November 2009 at 9:02 pm #

    Well now I have taken my dog out of PetSmart and into a pet hospital where he is in intensive care. They have given him a SNAP test, critical care exam, tick borne PCR, ultrasounds, Xrays, pain medication, an MRI but had to wake him from the anaesthesia because he was short of breath. The only thing they know for sure is that his pain is coming from his back and neck which a neurological specialist feels that it could be neurological. He also has abdominal pain and his ribs hurt on his left side. They have told me that tomorrow they want to run more Xrays on his abdomen to see why he’s in pain even though PetSmart has taken those Xrays prior because they said that maybe there will be a changein the Xrays. Other than that they said that he is responsive, has been eating, and does not have diarrhea but is on pain medication. Was not able to see him on the weekend because they don’t allow visitation on the weekend. I will see him tomorrow and my bill is up to $6000.00… I am frustrated and I am running out of money. I love him dearly and do not want to lose him because of money.

  102. melisa cortez 12 November 2009 at 2:21 pm #

    Hi, I’m looking for some answers for my dog Marley. He is a Yorkie that weighs 11.60 lbs. He had 2 skin masses that were to be removed today, Thursday at 7am at Banfield. The gave him a shot of Convenia (80mg/ml) yesterday at 6pm… By 10 pm. my dog was acting rather strange. He looked doped up and was shaking. By 3 am. he could not stand on his 4 legs and kept falling over. I took him to Banfield today at 7am. and they have been running all sorts of test (Blood work, x-rays, checked his bladder, and now have administered pain medications) and have found nothing. My bill is up to $500.00 and they need to run more tests. My dog is 7 years old and will be 8 in dec….. Do you have any advice before I have a nervous breakdown?

    • Dr. James W. Randolph 13 November 2009 at 2:06 pm #

      There are a jillion possibilities, which is why the doctors at Banfield are running tests and taking radiographs. It could be a quirk of his response to the anesthetic, or a change in his demeanor and metabolism as the anesthetic wore off. I doubt that Convenia is a factor, as we might expect vomiting and loss of appetite if it were, but not shaking and ataxia. Without the test results I can’t help much, but I would certainly be interested in knowing what the doctors find and how he is recovering. By the way, 8 is not old for most Yorkies.
      Best wishes,
      Dr. Randolph

  103. Kathy 21 October 2009 at 6:10 pm #

    My kitty had a shot of Convenia yesterday morning…She has not been eating, and sleeping all the time and had a fever…it has been about 30 hours and she is no better.

  104. Joanne 9 October 2009 at 11:38 pm #

    My Puggle Herkie got a shot of Convenia last Wednesday, and after that he got a fever. I was wondering if it’s a side effect of the shot. The fever comes and goes but it’s been 3 days already. I am just worried. We went to Banfield 3 weeks ago because Herkie got stung by a bee and his lower lip got swollen. The oral antibiotics didnt work so we when back and they gave him Convenia. I hope he will feel better and the swollen lip gets better.

    • Dr. James W. Randolph 10 October 2009 at 12:48 pm #

      Joanne, several things about poor Herkie’s story bother me. No, fever is not a side effect of Convenia. How HIGH is the fever? A swollen lip from a bee sting should resolve in less than 3 weeks, usually in a day, certainly by three days. There may be a complicating factor, such as the stinger still being in place, OR the bee sting was a coincidence and the REAL cause of the swelling is something else. I would recommend that you either take him back to the doctor for more aggressive diagnostics or seek a second opinion. Please keep us posted on Herkie’s progress and findings.
      Dr. Randolph

  105. Julie Davenport 25 September 2009 at 9:40 am #

    My cat was diagnosed with a UTI and blood in his urine. I took him in Wednesday to get a shot of Convenia since I could not get the oral medication into him. Now he can barely walk a few steps without wobbling and falling over and crying in pain. Is this something to be concerned about or is it normal after an injection? How concerned should I be that he is not eating or drinking. This started on Sunday and he has only eaten a few bites since then.

    • Dr. James W. Randolph 25 September 2009 at 10:57 pm #

      “Is this something to be concerned about…”
      Yes, Julie, you should be very concerned. Your kitty should have seen his doctor on Monday with these signs, as he may have an obstructed urinary tract, adverse reaction to medication or other complication. I will send you an e-mail as soon as I finish this reply, recommending you take him to your local emergency hospital tonight. Please write back to let us know how he fares. This is very serious.

  106. Misty Leftwich 16 September 2009 at 9:58 am #

    My dog was originally diagnosed with kennel cough. Her symptoms of coughing, sneezing, moderately hacking, retching, gagging, lethargy, depression, spaced-out, no interest in much, poor appetite continued for a month and to this day now almost going on two months. Then I went to a specialist. More chest X-rays were done, and they concluded bronchitis. Previously she was given oral antibiotic that she continuously threw up. They consisted of, Azithromycin and some other one that I can’t think of the name of at the moment. They said since her reaction to oral medication wasn’t going well she was given this injectable antibiotic, Convenia yesterday. This morning she threw up all her food, and my first thought was “Oh no, it’s happening again…intolerance to an antibiotic. She is so weak and has lost a lot of weight. I was having high hopes that this treatment would work and help kill the infection she has. Although, would this even knock out an infection such as bronchitis or kennel cough? They say her lungs are inflamed. Second, do you think this symptom of throwing up her food will go away? She desperately needs to put some weight on!
    If this injection doesn’t work for her, what are my alternatives to get rid of bronchitis? Please help, she has felt so bad the last two months, and I know she is running out of time. The poor girl has to be picked up and taken to the bathroom because she is too weak to walk. Any information would be greatly appreciated.

    • Dr. James W. Randolph 17 September 2009 at 4:06 pm #

      Misty, that your dog was initially diagnosed with “kennel cough,” (the proper term is infectious tracheobronchitis (ITB), because the vast majority of so-called “kennel cough” patients have never even seen a kennel) is not surprising. I will cover ITB in an upcoming post. It’s a common condition and all of the signs your pet exhibited fit the syndrome. The vast majority of such patients respond to therapy, resolve, and do fine. Your dog, however, seems to have more than just ITB going on.
      1. There may or may not be infection in the airway, and the only way to know is by tracheobronchial lavage (sometimes called transtracheal wash) followed by cytology and bacterial culture and sensitivity. Was this procedure done? What were the cytology results? What were the culture and sensitivity results?
      2. “lungs are inflamed.” Strictly speaking, lungs are not involved in ITB, or pure bronchitis. A cause for the inflamed lungs needs to be determined and this may require lung biopsy.
      3. In FDA approval trials about 5% of Convenia-injected patients experienced vomiting and loss of appetite. Read the above-linked MyPetsDoctor.com post and you’ll better understand what those numbers really mean.
      4. “will the symptom of throwing up her food go away?
      a. Your specialist (whom, I assume, is a board-certified internist) is probably considering the possibility that there are gastrointestinal problems, separate from the respiratory tract problems, that are causing the vomiting.
      b. He is likely also considering an intravenous (IV) antibiotic, though even this route may cause vomiting.
      5. That your pet is “too weak to walk” is a grave sign, which I assume the specialist is addressing aggressively.
      Please keep us posted on your pet’s progress, and our readers and I will be eagerly awaiting the outcome.
      Best wishes,
      Dr. Randolph

  107. Meryl 8 September 2009 at 8:11 am #

    My 15 year old female cat stopped eating so the veterinarian did a geriatric blood panel. She was diagnosed with high liver enzymes – AST is 172 and ALT is 495. They did an ultrasound and found a probably benign cyst in her liver. We tried Denamarin and oral antibiotics. They didn’t work, but one day she had an injury to her paw – probably bitten by another cat-and the veterinarian gave her Convenia. That was over two weeks ago and now she eats well and seems to be feeling much better. We haven’t tested her liver again because she’s doing well. Do you think the Convenia cured her?

    • Dr. James W. Randolph 8 September 2009 at 3:13 pm #

      Meryl, this is a real chicken-and-egg question. Which came first, the liver problem or the loss of appetite? We will never know. When cats stop eating their livers undergo a unique process that doesn’t occur in all species…the liver begins to suffer storage of fat. The fat then slows down the movement of bile through the liver, which can elevate liver enzymes and cause inflammation and death of liver cells. The combination of Denamarin and other SAM-E neutraceuticals with antibiotics is a common and accepted method of dealing with liver disease when a liver biopsy is not practical or available. IF the liver problem was caused by INFECTION and the infection was not sensitive to the oral antibiotic(s) used but WAS sensitive to Convenia’s ingredient, Convenia might be able to take credit for improvement. The first antibiotic(s) might have knocked down the infection and Convenia finished it off. Or Covenia knocked it down enough that she is no longer clinical. Does that mean she is cured? Maybe, maybe not. Another set of blood tests (with CBC and differential along with the chemistry panel) would tell you more, and a liver biopsy would tell you the most. Do you want to subject a 15-year old well kitty to a liver biopsy? I probably wouldn’t, unless she relapsed, but it’s the only way to know exactly what’s going on in the liver. Please write back when you have the followup lab test results.
      Best wishes,
      Dr. Randolph

  108. Andrea 13 August 2009 at 10:36 am #

    Hello Dr. Randolph,
    I have a very beloved 6 year old foster cat, Malachi, who has been in renal failure since birth. He has recently developed his 2nd antibiotic resistant infection this year. The first followed a bad tooth abscess and spread to his sinus cavity. He had no response to Clavamox, Clindamycin or Baytril. Eventually Azithromycin worked. This time his veterinarian sees no oral issues, it just seems to be a sinus infection with much swelling around the nose/eyes and bloody discharge. Azithromycin has not worked and on Tuesday he got a Convenia injection. A day and a half later I see no improvement. Should I wait? Request something else? I very much appreciate any advice you can give me. Thank you, Andie

    • Dr. James W. Randolph 13 August 2009 at 10:19 pm #

      Thank you for your very difficult question, Andie. Clearly Malachi has immune system issues to go along with his other problems. Chances are good that he has a viral component to his nasal discharge and immune stimulants such as Enisyl may help. For the bacterial component of the infection (if, indeed, there is one) the BEST approach is bacterial culture and sensitivity test. Malachi will need to be off his Azithromycin for a few days, then a sample taken, after which he can restart his Azithromycin until the results come in, about 3-10 days. The sinuses may have to be radiographed and/or ultrasounded to determine whether masses are impeding natural flow of normal fluid production from the sinuses’ linings. All in all, it’s complicated, and could be very expensive. Please keep us updated and let us know how Malachi fares. Thank you for your question and your readership of MyPetsDoctor.com.

  109. Di 5 August 2009 at 2:30 pm #

    My 15 yr. old cat developed horrible sores on her eye lid, as well as swelling inside her nose, distorting her face a bit. Now, she’s got a large ball on her mouth. They assume it’s tumors, with possible secondary infections, but they’ve been giving her Convenia and now steroids too. This actually has helped with the swelling and issues, with always come back. Should I continue to give her the meds, a 3rd time. Is it even more dangerous to her to do that?

    • Dr. James W. Randolph 5 August 2009 at 6:40 pm #

      There is unlikely to be any harm to the palliative therapy you’ve described. Convenia makes it easy to have ongoing antibiotic therapy without having to hassle her with oral medications. The corticosteroids may give some reduction of size of the tumors. Of course, I’m sure you are aware that none of this is going to be curative. The lesions sound very invasive, which, I assume, is why you and your pet’s doctor have chosen a palliative approach instead of a more aggressive approach.
      Best wishes with her, and please keep us informed of her progress,
      Dr. Randolph

  110. Kate 27 July 2009 at 12:51 pm #

    I moved to a new state a few weeks ago. I took my cats to their former vet before we left for a routine visit. Their vaccinnations were updated and other than needing teeth cleanings sometime soon, all was okay with their exams. Since we’ve been in our new home, one of them has been lethargic and losing weight. I’m not sure she’s eating. I took her to the vet this morning, where they said it could be stress, a virus or her kidneys or liver. She is at least 8 yrs old, but maybe older. She wouldn’t let them take blood. He gave her injections of Convenia and Dexamethasone, and said to isolate her from my other cats to better monitor her water and food consumption, litterbox and any vomiting (which there has been none of so far). He said if she’s not improved in a day or so, bring her back, and they will knock her out with gas to take blood. He said the condition of her teeth was not bad enough to cause her not to eat. She and all my cats have been informally diagnosed with feline herpes, but none of them are exhibiting symptoms right now of that or respiratory problems. She has a fever. All my other cats are healthy, and they are all indoor cats. Do you have any other advice? Thank you!

  111. Carol 22 July 2009 at 9:10 am #

    Hi Dr. Randolph…
    My kitty (2 yrs old) was diagnosed with an upper respiratory infection just last night. He was given a shot of Convenia for the secondary bacterial infections and a shot of anti-inflammatory. Last night he had some vomiting. I don’t want to be an alarmist and call the vet again so soon. Would some vomiting be typical? (All his vitals were ok last night and he was not running a fever.
    Also, upon reading about URTIs, it sounds like he would have had to be around an infected cat to catch this. He is in a single-cat household, outside during the day and brought in at night. I am just wondering how he got it.
    Thanks for any insight into this.
    Carol

    • Dr. James W. Randolph 22 July 2009 at 10:00 pm #

      Thank you for your questions, Carol. Vomiting is common in upper respiratory tract infection cases as the inflammation of the trachea, pharynx and nasopharynx often stimulate gagging, which leads to vomiting.
      As to where your kitty got the infection the answer is in your question, “outside during the day.” He may have had even passing contact with an infected cat (and the infected cat may be asymptomatic). Feel free to write back if more questions arise, and NEVER be hesitant to call your pet’s doctor’s office…that’s what we’re here for!

  112. Gail Hutchin 13 July 2009 at 2:09 pm #

    Two of our cats have used Convenia with great results after surgery or with infections. Does Convenia work on URIs? I only know that the cat I’m volunteering with is sneezing and coughing a lot. There is a discharge of mucus and a little blood when he sneezes. Does Convenia work on secondary infections from viruses, such as lung infections?
    Thanks,
    Gail

    • Dr. James W. Randolph 14 July 2009 at 8:31 pm #

      Officially, Convenia is approved for use in skin infections. The cephalosporin family of antibiotics has great use in killing bacteria in and on the skin. I have used Convenia twice in upper respiratory tract infections in cats with good success, but twice does not a clinical trial make! By definition, “lung” infections don’t qualify as UPPER respiratory tract infections and I haven’t tried Convenia on pneumonia. Thank you for caring for God’s creatures through your fostering efforts. Best wishes and thank you for your question and your readership of MyPetsDoctor.com, Dr. Randolph.

  113. Shanan 17 June 2009 at 12:51 pm #

    My dog was given Convenia yesterday for infection. Later we discovered she had ingested warfarin. Had blood transfusion last night, got her blood to clot, extremely dehydrated this morning, and CBC showed her WBC at 40000. He is putting her on another antibiotic. Shouldn’t the Convenia have kicked in by 24 hours? Her lower lung was full of blood and the xrays this morning showed some improvement.

  114. Canan Orhun 17 June 2009 at 7:53 am #

    My cat has been acting strange for 3 days: vomiting, eating less, staying in for long hours, cleaning his bottom more often usual. The vet today has taken a blood sample and administered Convenia. Unfortunately I have not been able to talk with the vet as she went into surgery, immediately after.

    Any thoughts on what may be wrong? I am having anxiety as I wait for the vet to talk with me later today.

    Thanks for your help.

    • Dr. James W. Randolph 17 June 2009 at 11:40 pm #

      There are literally thousands of possibilities, and only the doctor who has examined and evaluated your pet should comment on those possibilities. Unfortunately, emergencies happen and sometimes pet owners are inconvenienced in having to wait for the emergency to be handled before getting the rest of the answers. Please, do write back and let us know what the doctor told you.
      Thanks for reading MyPetsDoctor.com,
      Dr. Randolph

  115. Evelyn Wiggs 11 June 2009 at 11:03 pm #

    My cat was acting odd, meaning she wasn’t eating like normal and she seemed to be wobbly some when she walked. She also has an infected eye. I took her to the Veterinarian and he checked her temperature which was normal. He gave her an injection of Convenia which I’m not familar with. She really didn’t seem any better today so I called him back and ask if there was anything I could get to give her over the weekend. He explained that this antibiotic stayed in your system for about 2 weeks and it would work on her gradually. How long should it be before I seee results and does this sound like the appropriate medicine. Thank you.

    • Dr. James W. Randolph 12 June 2009 at 2:48 pm #

      Thank you for writing to MyPetsDoctor.com. When to expect a response depends mostly on what was wrong with your kitty. If you could write us back with the diagnosis that might help. However, if you are not seeing SOME improvement by Monday I would be in touch with the doctor. He may need to perform some laboratory tests such as Complete Blood Count (CBC), Chemistry Profile and Urinalysis. She may also need a Feline Leukemia Virus and Feline Immunodeficiency Virus test. Feel free to write back with an update, or more questions should they arise.
      Thanks for reading MyPetsDoctor.com, Dr. Randolph

  116. G.T.McKinney 17 May 2009 at 1:24 pm #

    Sir, my vet administered the long lasting Convenia to my fourteen year old dog. He is drinking water well enough but his appetite has dropped drastically. We can get him to only take a few morsels of his favorite dog food at a time. Hardly nothing at all. This is starting to worry us. My question, is this a side effect from the shot and if so, how long would you estimate before he regains his appetite? Thank you very much. G.McKinney

    • Dr. James W. Randolph 17 May 2009 at 10:46 pm #

      Loss of appetite is an unusual side effect of Convenia, occurring in less than 7% of cases during approval clinical trials. It is more likely that the disease process for which your pet’s doctor is using Convenia is causing the loss of appetite. Call him first thing Monday morning and discuss this complication with him. He may need to see your pet for followup.


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