Convenia Long-Acting Antibiotic Injection

“Awwww, Doc, can’t you just give him a shot?”

Usually that question comes from a pet lover in the form of an objection to having to give oral medications for a two week or longer time period. Up until now our answer has been, “No, an antibiotic injection will last 12 to 24 hours, then we would have to give another one. Do you want to come in every day for 14 days for injections at $35.00 each?”

But the times, they are a’changing.

Enter Convenia, (cefovecin sodium) the long-acting antibiotic from Pfizer Animal Health that lasts 10 to 14 days with a single injection. Convenia is more than just penicillin. It’s a broad-spectrum antibiotic (in the simplest terms that means it kills a lot of different kinds of bacteria), so it can be used in a wide variety of infected organ systems and clinical and hospital situations.

Convenia isn’t right for every infection. If it were, it would be the only antibiotic on the market. Instead, there are hundreds and hundreds of antibiotics, each with a situation or organism on which it works best.

If my pet were a patient, I would sure ask my pet’s doctor if Convenia (cefovecin sodium) were right for him.

covenia, convina, convinia, covinia


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  1. Dr. Randolph,
    I took my five month old cat tux to the vet today because after several days of unsuccessful at home treatment he had developed a nasty cough followed by a hard swallow. Several days prior to this he had minimal eye discharge, a snotty nose that turned into a dry stuffy nose and lots of sneezing. The vet gave him a shot of convenia and dexamethasone. This was nearly 12 hours ago and I have seen little to no improvement in his condition. The vet said he had an upper respiratory infection that likely developed into bronchitis. My question is should I be alarmed at the lack of improvement and call the vet back and let them know or should I wait? If so, how long will it take for him to show any signs of improvement? Thank you in advance for taking the time to read my question?


    Candice Jones

    • Several factors: First, 12 hours is MUCH too fast to expect a sick patient to feel better. Second, upper respiratory disease of cats can be bacterial, viral, chlamydial or mycoplasmal, and, rarely, fungal and even foreign-body related. Antibiotics can help ONLY with bacterial infection, and not all bacteria are susceptible to Convenia. Bronchitis may predispose Tux to pneumonia, so, stay in touch with your veterinarian in case Tux needs additional care. Thanks for reading, Dr. Randolph.

  2. My 12 year old rottie was operated on for bloat. Clindamycin makes her sick. Will convenia injection be an alternative

  3. Hi Dr Randolph,

    Do you think Convenia would be helpful for a rat with pneumonia? She is currently on Synulox (Amoxycillin) oral drops, but she tries to hold it in her mouth and not swallow, and won’t eat food that we mix it in. She is only 8 months. My vet told me about long-lasting injectable ABs but I only just found out the name. She said they can’t get it at the moment (we are in the UK). Thank you.

    • I’m sorry, but I’ve had very little experience with rodent medicine. In general, the cephalosporin family of antibiotics is not effective in the respiratory tract. Thanks for reading, Dr. Randolph.

  4. My dog (13 male) just had double TECA surgery. I can’t get him to take his meds from the surgeon – I was given 3 mandatory & 1 to use as needed (to keep him calm). One is a liquid (for inflammation & pain) that I finally got him to take tonight in pumpkin puree, but the pills start to dissolve in the wet food, then he tastes it (probably bitter) and refuses to eat anymore. I’m not so much worried about the codeine (pain reliever) as hopefully the anti-inflammatory/pain combo will be enough (he’s not whining or appearing in pain). But I am concerned about him not taking the antibiotic. Do you think Convenia would be a good solution? I only have one hand so can’t really force things in his mouth – plus he’s been nippy/biting since the surgery when anyone tries that. Thanks!

    • Convenia is a good antibiotic for infections of the skin, but only his veterinarian can make the call on whether it’s appropriate in this situation. And, you’re going to have to talk to the doctor to get a Convenia injection anyway, so give them a call. Thanks for reading, Dr. Randolph.

  5. Convenia was a suggested antibiotic for aspiration pneumonia in yorkie puppies. What are your thoughts on this and have you heard of there being success for administering convenia in this manor? Is there an age/weight guideline in small breed puppies? Yorkie puppies as small as 3 ounces and up. What are the side effects?